Evidence map›Paper›PMID 41646786›Full record

ArticlemedRxiv : the preprint server for health sciences2026

The Effects of Mindfulness Meditation on Burnout in Clinical Genetic Counselors: A Three-Arm Randomized Controlled Trial.

Colleen Caleshu, MaryAnn Campion, Jehannine J Austin, Philippe Goldin, Julia Silver, Aad Tibben

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Colleen CaleshuGenome Medical, South San Francisco, CA, USA.
MaryAnn CampionStanford University School of Medicine, Department of Genetics, Stanford, CA, USA.
Jehannine J AustinUniversity of British Columbia, Departments of Medical Genetics and Psychiatry, Vancouver, BC, Canada.
Philippe GoldinBetty Irene Moore School of Nursing, University of California, Davis.
Julia SilverUniversity of California San Francisco, Prenatal Diagnostic Center, San Francisco, CA, USA.
Aad TibbenCentre for Human and Clinical Genetics, Leiden University Medical Centre (LUMC), Leiden, The Netherlands.

Funding

Stanford Center for Clinical & Translational Education and Research (Spectrum)UL1TR003142 · NCATS · STANFORD UNIVERSITY · PI O'HARA, RUTH M · 2019 to 2023
$45.0M
NCATS NIH HHS UL1 TR003142
6 · The paper itself

Abstract

Burnout is common among genetic counselors (GCs). Clinician burnout has been found to adversely affect individual well-being, patient care, and likelihood of staying in a role. Both individual and systems solutions are needed to address clinician burnout. Mindfulness meditation (MM) is one individual-level solution that has shown promise for reducing burnout in other clinicians but has not been studied in GCs. We conducted a decentralized, parallel, three-arm randomized controlled trial comparing MM to a novel active control meditation (ACM) and a no-meditation control (NMC), with 1:1:1 randomization. Participants were clinical GCs in the US. MM and ACM participants were asked to do 10 minutes of daily app-based meditation for 8 weeks. ACM was designed to control for non-specific aspects of MM by mimicking MM length and structure without including mindfulness techniques. The primary outcome, burnout, was assessed using the Professional Fulfillment Index. Secondary outcomes included other indicators of professional well-being, such as stress and professional fulfillment. Outcomes were assessed via an intention-to-treat approach, with multiple imputation for missing outcome data. Outcome analyses controlled for baseline trait mindfulness. 397 participants (mean age 33 years; 97.7% female, 94.2% White) were randomized, and 76% completed post-intervention outcome measures. There was no difference in burnout reduction between MM and ACM groups (p = 0.44). However, multiple measures suggest that ACM did not perform well as an inert active meditation control, thus the primary hypothesis could not be effectively tested. In pre-planned secondary analyses, MM reduced burnout (Cohen's d = -0.84, p < 0.001) compared to NMC, a passive control. Similar results were seen for stress. These findings suggest MM may be beneficial for GC professional well-being; however, further research on MM for GCs is needed with more diverse study samples and better active controls.

Identifiers

PMID41646786
PMCPMC12870655

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.