SynthesisFrontiers in pharmacology2025
Efficacy and safety of oral proprietary Chinese medicines in the treatment of stable chronic obstructive pulmonary disease: a network meta-analysis.
Synthesis in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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4 authors.
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Abstract
Background: A variety of oral proprietary Chinese medicines (OPCMs) have clinical efficacy in the adjunctive treatment of stable chronic obstructive pulmonary disease (COPD). However, the OPCM with the best therapeutic effect is not yet clear. Thus, a network meta-analysis (NMA) is leveraged to evaluate the best efficacious OPCM for the adjunctive treatment of stable COPD. Methods: Randomized controlled trials (RCTs) related to the adjunctive treatment of stable COPD with OPCMs were searched in PubMed, Web of Science, Embase, Cochrane Library, China National Knowledge Infrastructure, Wanfang, and VIP. The search period was up to 1 April 2024. Study screening and data extraction were performed according to predefined inclusion and exclusion criteria. The assessment of bias in the included studies was carried out using the Cochrane risk of bias tool version 2 (RoB 2.0). Statistical analyses were performed utilizing Stata version 17.0 (64-bit) and R software (version 4.3.3). Results: The database retrieval yielded 7,572 articles in total. Ultimately, 64 articles were included in the analysis. Compared to routine treatment (RT), the Yi-qi-gu-biao pill_RT improved the forced expiratory volume one-forced vital capacity (FEV Conclusion: Based on the current findings, no specific OPCM has demonstrated noticeable effects across multiple aspects. However, it is evident that OPCM holds considerable potential as an adjunctive treatment for patients with stable COPD. Future high-quality and well-designed RCTs are necessary to further validate our findings. Systematic Review Registration: https://www.crd.york.ac.uk/PROSPERO/view/CRD42024511142.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.