Evidence mapPaperPMID 41646993Full record

ArticleiGIE : innovation, investigation and insights2023

Long-term outcomes (≥3 years) after gastric peroral endoscopic myotomy for refractory gastroparesis: a systematic review and meta-analysis.

Andrew Canakis, Smit S Deliwala, Michael Frohlinger, Justin P Canakis, Douglas G Adler

Abstract read
In one paragraph

Article in iGIE : innovation, investigation and insights, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Andrew CanakisDivision of Gastroenterology and Hepatology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Smit S DeliwalaDivision of Gastroenterology and Hepatology, Emory University School of Medicine, Atlanta, Georgia, USA.
Michael FrohlingerDepartment of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Justin P CanakisDepartment of Medicine, George Washington University School of Medicine and Health Sciences, Washington, DC.
Douglas G AdlerCenter for Advanced Therapeutic Endoscopy (CATE), Porter Adventist Hospital, Denver, Colorado, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Gastric peroral endoscopic myotomy (G-POEM) has emerged as a novel management option for patients with refractory gastroparesis. Although G-POEM has shown excellent short-term outcomes, clinical success with symptom resolution in the long-term setting is still being investigated. As such, our aim was to investigate long-term outcomes after G-POEM in patients with gastroparesis. Methods: Multiple databases were searched from inception until March 2023 for studies looking at long-term outcomes (≥3 years) for patients with gastroparesis treated with G-POEM. The primary outcome was clinical success 3 years after G-POEM. Secondary outcomes included changes in Gastroparesis Cardinal Symptom Index score before and 36 months after G-POEM, technical success, adverse events, and length of hospital stay. Quality assessment of studies was performed by using the Qumseya scale. Results: Five studies were included with 560 patients (average age, 47.03 years; 67.8% female) over a mean follow-up of 38.4 months. The pooled rate of clinical success at 36 months was 75% (95% confidence interval [CI], 68.2-80.5; Conclusions: G-POEM has a durable long-term clinical success rate. Further studies are needed to identify patient selection factors that will enhance its clinical success.

Identifiers

PMID41646993
PMCPMC12850717

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.