Evidence map›Paper›PMID 41647255›Full record

ArticleNAR molecular medicine2026

A prevalent disease-associated SNP in the human

Christopher A Henderson, Brett P Ransegnola, James Garmey, Ali Khan, Rédouane Aherrahrou, Michael Purdy, Shijie Wu, Andrea Zhou, Jennifer L Kirby, Michael J Lipinski and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NAR molecular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Christopher A HendersonBeirne B. Carter Center for Immunology Research, University of Virginia School of Medicine, Charlottesville, VA 22903, USA.
Brett P RansegnolaBeirne B. Carter Center for Immunology Research, University of Virginia School of Medicine, Charlottesville, VA 22903, USA.ORCID https://orcid.org/0000-0002-5886-3437
James GarmeyBeirne B. Carter Center for Immunology Research, University of Virginia School of Medicine, Charlottesville, VA 22903, USA.
Ali KhanMedical Scientist Training Program, University of Virginia School of Medicine, Charlottesville, VA 22903, USA.
Rédouane AherrahrouDepartment of Biomedical Engineering, University of Virginia School of Medicine, Charlottesville, VA 22903, USA.
Michael PurdyDepartment of Molecular Physiology and Biological Physics, University of Virginia School of Medicine, Charlottesville, VA 22903, USA.
Shijie WuBeirne B. Carter Center for Immunology Research, University of Virginia School of Medicine, Charlottesville, VA 22903, USA.
Andrea ZhouRobert M. Beirne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, VA 22903, USA.
Jennifer L KirbyMedical Scientist Training Program, University of Virginia School of Medicine, Charlottesville, VA 22903, USA.
Michael J LipinskiMedical Scientist Training Program, University of Virginia School of Medicine, Charlottesville, VA 22903, USA.
Vicki GordonBeirne B. Carter Center for Immunology Research, University of Virginia School of Medicine, Charlottesville, VA 22903, USA.
Mark YeagerDepartment of Molecular Physiology and Biological Physics, University of Virginia School of Medicine, Charlottesville, VA 22903, USA.
Mete CivelekDepartment of Biomedical Engineering, University of Virginia School of Medicine, Charlottesville, VA 22903, USA.
Coleen A McNamaraBeirne B. Carter Center for Immunology Research, University of Virginia School of Medicine, Charlottesville, VA 22903, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The helix-loop-helix transcription factor ID3 is a critical regulator of tissue development and homeostasis. Aberrations in ID3 are strongly associated with numerous human disease processes including Burkitt's lymphoma. We previously identified that a single-nucleotide polymorphism (SNP) in

Identifiers

PMID41647255
PMCPMC12869245

What Socratic holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.