Evidence map›Paper›PMID 41648540›Full record

ArticlebioRxiv : the preprint server for biology2026

The Vesicular Glutamate Transporter Modulates Sex and Region-Specific Differences in Dopaminergic Neuron α-Synuclein Toxicity by Modifying Cytosolic Dopamine Levels.

Kevin Garzillo, Mia Perulli, Daniel T Babcock

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kevin GarzilloDepartment of Biological Sciences, Lehigh University, Bethlehem PA, United States.ORCID 0000-0002-7144-3955
Mia PerulliDepartment of Biological Sciences, Lehigh University, Bethlehem PA, United States.
Daniel T BabcockDepartment of Biological Sciences, Lehigh University, Bethlehem PA, United States.

Funding

Selective Vulnerability of Dopaminergic Neurons in DrosophilaR03NS144936 · NINDS · LEHIGH UNIVERSITY · PI Daniel T. Babcock · 2025 to 2026
$155k
NINDS NIH HHS R03 NS144936
6 · The paper itself

Abstract

Parkinson's disease disproportionately affects males; however, the cause of this sex difference is unknown. We found that expressing mutant α-synuclein

Indexed as

DopamineMitochondriaNeurodegenerationParkinson’s DiseaseSelective VulnerabilitySex Differencesvesicular glutamate transporterVGLUTα-synuclein

Identifiers

PMID41648540
PMCPMC12871730

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.