Evidence map›Paper›PMID 41648658›Full record

ReviewESMO real world data and digital oncology2024

Digital twins: a new paradigm in oncology in the era of big data.

L Mollica, C Leli, F Sottotetti, S Quaglini, L D Locati, S Marceglia

Abstract readReview
In one paragraph

Review in ESMO real world data and digital oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Mapping the future of medicine through digital twins.Frontiers in molecular medicine · 2026
    Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

L MollicaMedical Oncology Unit, Istituti Clinici Scientifici Maugeri IRCCS, Pavia, Italy.
C LeliMedical Oncology Unit, Istituti Clinici Scientifici Maugeri IRCCS, Pavia, Italy.
F SottotettiMedical Oncology Unit, Istituti Clinici Scientifici Maugeri IRCCS, Pavia, Italy.
S QuagliniDepartment of Electrical, Computer and Biomedical Engineering, University of Pavia, Pavia, Italy.
L D LocatiMedical Oncology Unit, Istituti Clinici Scientifici Maugeri IRCCS, Pavia, Italy.
S MarcegliaDepartment of Engineering and Architecture, University of Trieste, Trieste, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent advancements in health care digitalization opened the collection and availability of big data, whose analysis requires artificial intelligence-based technologies to facilitate the development of predictive tools supporting decision making in clinical practice. In this context, the idea of constructing 'digital worlds' to evaluate the performance of such novel tools becomes more attractive. Digital twins (DTs) are 'digital objects' characterized by a bi-directional interaction with their 'real-world counterparts'. DTs aim to enhance predictions further by leveraging both the predictive capabilities of digital simulations and the continuous updating of real-life data-ideally incorporating clinical records, multiomics data, and patient-reported outcomes. DTs can potentially integrate these diverse data into virtual models applicable across pre-clinical to clinical studies. Running simulations

Indexed as

artificial intelligencebig datacancer patientclinical oncologydigital twins

Identifiers

PMID41648658
PMCPMC12836754

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.