Evidence map›Paper›PMID 41648663›Full record

ArticleFrontiers in neurology

Identification of symptomatic carotid plaque by CTA-based radiomics: a multicenter study.

Wei Zhang, Zongmeng Wang, Qiaomei Xu, Xi Wang, Le Zhang, Rong Chen, Mingsha Liao, Jianquan Zhong

Abstract read
In one paragraph

Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wei ZhangDepartment of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China.
Zongmeng WangDepartment of Radiology, Zigong First People's Hospital, Zigong, Sichuan, China.
Qiaomei XuDepartment of Radiology, Zigong First People's Hospital, Zigong, Sichuan, China.
Xi WangDepartment of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China.
Le ZhangDepartment of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China.
Rong ChenMedical Imaging Center, Second People's Hospital of Yibin, Yibin, Sichuan, China.
Mingsha LiaoDepartment of Radiology, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.
Jianquan ZhongDepartment of Radiology, Zigong First People's Hospital, Zigong, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To develop and validate a combined model integrating traditional clinical characteristics, imaging features and radiomic features based on head and neck computed tomography angiography (CTA) to predict ischemic events in ipsilateral cerebral vessels. Methods: In this multicenter retrospective study, 223 patients from 3 independent centers were divided into training set ( Results: Univariate analysis and multivariate logistic regression analysis showed that platelet distribution width (PDW) (odds ratio [OR] = 0.88; 95% confidence interval [CI], 0.80-0.97) and plaque ulceration (OR = 5.67; 95% CI, 2.86-11.23) were independently related to symptomatic plaque. Twelve radiomic features significantly related to symptomatic plaque were selected. The combined model demonstrated superior performance compared with both the radiomic model and the traditional model, the AUCs of the training set and internal test set were 0.819(95% CI: 0.749-0.888) and 0.785(95% CI: 0.620-0.950), and also demonstrated robust performance in external validation set (AUC: 0.868; 95% CI: 0.765-0.970). Conclusion: The Combined model demonstrated the highest diagnostic performance in identifying symptomatic plaque, which helps clinicians to analyze patients' condition more comprehensively and provides additional value for identifying high-risk individuals and improving prognosis.

Indexed as

carotid atherosclerosiscomputed tomography angiographyischemic strokeradiomicssymptomatic plaque

Identifiers

PMID41648663
PMCPMC12867918

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.