Evidence map›Paper›PMID 41649644›Full record

ArticleVeterinary research communications2026

Integrative analysis of genetic, biochemical, and microbial factors in camel calf diarrhea.

Ahmed Elsayed, Amani A Hafez, Mohamed T Ragab, Marwa A Fawzy, Adel M El-Kattan, Ahmed I Ateya

Abstract read
In one paragraph

Article in Veterinary research communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Pneumo-/enteritis in dromedary camels (Frontiers in veterinary science · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ahmed ElsayedDepartment of Animal Health and Poultry, Animal and Poultry Production Division, Desert Research Center (DRC), Cairo, 11753, Egypt. decernes@yahoo.com.ORCID http://orcid.org/0000-0001-5049-3964
Amani A HafezDepartment of Animal Health and Poultry, Animal and Poultry Production Division, Desert Research Center (DRC), Cairo, 11753, Egypt.
Mohamed T RagabDepartment of Animal Health and Poultry, Animal and Poultry Production Division, Desert Research Center (DRC), Cairo, 11753, Egypt.
Marwa A FawzyDepartment of Animal Health and Poultry, Animal and Poultry Production Division, Desert Research Center (DRC), Cairo, 11753, Egypt.
Adel M El-KattanDepartment of Animal Health and Poultry, Animal and Poultry Production Division, Desert Research Center (DRC), Cairo, 11753, Egypt.
Ahmed I AteyaDepartment of Development of Animal Wealth, Faculty of Veterinary Medicine, Mansoura University, Mansoura, 35516, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diarrhea, though a clinical symptom, poses a major veterinary concern in camel calves due to high morbidity, mortality, growth retardation, and economic losses. This study investigated key bacterial enteropathogens, coding mutations, gene expression, and serum biochemical/antioxidant profiles in 35 healthy and 35 diarrheic camel calves. Fecal analysis using multiplex PCR identified Salmonella spp., Clostridium perfringens, Proteus spp., and Escherichia coli with distinct virulence genes (e.g., papC, eaeA, iutA, hilA, sopB, plc, ureC). Diarrheic calves showed significant upregulation of immune-related genes (IL-8, IL-17, TLR4, TNFα, PIN1, IER3, UBD, TECPR1) and downregulation of antioxidant markers (PRDX2, SOD3, CAT, Nrf2), alongside sequence variations. Biochemically, diarrheic calves exhibited elevated serum AST, ALT, ALP, urea, creatinine, potassium, and MDA, with reduced glucose, total protein, calcium, phosphorus, magnesium, sodium, chloride, and SOD. These findings highlight the multifactorial etiology of diarrhea, linking bacterial virulence with metabolic and oxidative stress alterations, providing insights for targeted prevention and therapeutic strategies in camel herds.

Indexed as

BacteriaCamelusDiarrheaAnimalsFecesVirulenceBiochemical profileCamelsDiarrheaEnteropathogensGene polymorphismsVirulence gene

Identifiers

PMID41649644
PMCPMC12881016

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.