Evidence map›Paper›PMID 41652613›Full record

ReviewJournal of nanobiotechnology2026

Sustainable nanomaterials for precision dental medicine: green synthesis, therapeutic applications, and future directions.

Al-Hassan Soliman Wadan, Mohamed Hany Ali, Doha El-Sayed Ellakwa

Abstract readReview
In one paragraph

Review in Journal of nanobiotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Al-Hassan Soliman WadanDepartment of Oral Biology, Faculty of Dentistry, Galala Plateau, Galala University, Attaka, 15888, Suez, Egypt. Alhassan.soliman.168@gmail.com.
Mohamed Hany AliFaculty of Medicine, Helwan University, Helwan, Cairo Governorate, Egypt.
Doha El-Sayed EllakwaDepartment of Biochemistry and Molecular Biology, Faculty of Pharmacy for Girls, Al-Azhar University, Cairo, Egypt. Profdoha@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sustainable nanomaterials are emerging as transformative platforms for precision dental medicine, uniquely combining environmental responsibility with individualized therapeutic performance. Green-synthesized metallic, polymeric, carbon-based, and bioactive nanomaterials exhibit superior biocompatibility, biodegradability, and a reduced ecological burden compared to conventionally produced analogues, while enabling enhanced antimicrobial, regenerative, and diagnostic capabilities. This review synthesizes recent advances in eco-friendly nanoparticle synthesis, life-cycle sustainability metrics, and the integration of nanotechnology into patient-specific diagnostics, controlled-release therapeutics, and regenerative dentistry. Emphasis is placed on biogenic routes for silver, gold, ZnO, chitosan, bioactive glass, cellulose nanocrystals, and lignin nanocarriers, as well as their clinical potential in caries management, periodontal regeneration, endodontic disinfection, implant surface engineering, and point-of-care diagnostics. Additionally, their compatibility with multi-omics-driven precision dentistry is highlighted. We further analyze safety profiles, biodegradation pathways, regulatory frameworks, and translational challenges related to standardization and AI-assisted personalization. Sustainable nano-platforms represent a strategic route to advance dental care toward predictive, preventive, and personalized practice while ensuring environmental stewardship and global healthcare equity.

Indexed as

DentistryGreen Chemistry TechnologyNanostructuresPrecision MedicineAnimalsHumansNanotechnologyGreen synthesis nanotechnologyNano-enabled oral diagnosticsPrecision dental medicineRegenerative dentistrySustainable nanomaterials

Identifiers

PMID41652613
PMCPMC12931040

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.