Evidence map›Paper›PMID 41653099›Full record

ArticleVeterinary medicine and science2026

Effect of Probiotic and Synbiotic Supplementation on Growth Performance, Serum Parameters and Gut Histomorphometry in Broiler Chickens Challenged With Eimeria.

Subash Chhetri, Dinesh Kumar Singh, Bibash Bahadur Tiwari, Sushil Neupane, Bikas Raj Shah, Deepak Subedi

Abstract read
In one paragraph

Article in Veterinary medicine and science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Subash ChhetriMinistry of Agriculture and Livestock Development, Kathmandu, Nepal.ORCID https://orcid.org/0009-0001-0657-9928
Dinesh Kumar SinghInstitute of Agriculture and Animal Science, Tribhuvan University, Kritipur, Nepal.
Bibash Bahadur TiwariDepartment of Animal Nutrition and Fodder Production, Faculty of Animal Science, Veterinary Science and Fisheries (FAVF), Agriculture and Forestry University (AFU), Rampur, Nepal.
Sushil NeupaneLivestock Services Section, Guthichaur Rural Municipality, Jumla, Nepal.
Bikas Raj ShahDepartment of Animal Sciences, College of Food Agriculture and Environmental Sciences, The Ohio State University, Wooster, Ohio, USA.ORCID https://orcid.org/0000-0001-7170-3887
Deepak SubediDepartment of Poultry Science, University of Georgia, Athens, Georgia, USA.ORCID https://orcid.org/0000-0002-0677-7094

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study evaluated the effects of probiotic and synbiotic supplementation on growth performance, serum biochemistry, immune organ development, intestinal length and histomorphometry in broilers challenged with Eimeria. A total of 360 Cobb 500 broilers were assigned to six treatment groups (3 replicates of 20 birds), and from Day 14 to 35, birds received water supplemented with either probiotic, synbiotic or control. On Day 14, challenged groups received a 10× dose of Eimeria from a commercial live vaccine. Data were analyzed using a 2×3 factorial ANOVA. Eimeria challenge significantly reduced average weight gain, final body weight and feed conversion efficiency. Intestinal morphology was adversely affected, as evidenced by decreased villus height (VH) and villus height to crypt depth ratio (VCR) in both the duodenum and jejunum. Eimeria challenge also induced significant alterations in serum biochemical parameters, including alkaline phosphatase, albumin, urea, lipase and triglyceride levels. Probiotic and synbiotic supplementation significantly improved relative spleen weight, intestinal length (jejunum, ileum, cecum) and villus morphology in all intestinal segments. Significant main effects of treatment were observed for growth and serum enzymes. Interaction between coccidiosis infection and treatment was significant for urea, and duodenal VH and VCR. Overall, probiotic and synbiotic supplementation mitigated the adverse effects of coccidiosis, with no significant differences observed between the two interventions.

Indexed as

ChickensCoccidiosisPoultry DiseasesProbioticsSynbioticsAnimal FeedAnimalsDietDietary SupplementsEimeriaIntestinesMalebroilercoccidiosisdrinking waterEimeriaprobioticsynbiotic

Identifiers

PMID41653099
PMCPMC12882558

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.