Evidence map›Paper›PMID 41654539›Full record

ArticleNature communications2026

Local PI(4,5)P

Giulia Russo, Nadja Hümpfer, Nina Jaensch, Steffen Restel, Christopher Schmied, Florian Heyd, Martin Lehmann, Helge Ewers, Volker Haucke, Michael Krauss

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Giulia RussoLeibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Germany.ORCID http://orcid.org/0009-0005-6321-6815
Nadja HümpferFaculty of Biology, Chemistry, Pharmacy, Freie Universität Berlin, Berlin, Germany.ORCID http://orcid.org/0000-0002-4349-4886
Nina JaenschFaculty of Biology, Chemistry, Pharmacy, Freie Universität Berlin, Berlin, Germany.
Steffen RestelLeibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Germany.
Christopher SchmiedLeibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Germany.ORCID http://orcid.org/0000-0003-2058-1124
Florian HeydFaculty of Biology, Chemistry, Pharmacy, Freie Universität Berlin, Berlin, Germany.ORCID http://orcid.org/0000-0001-9377-9882
Martin LehmannLeibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Germany.ORCID http://orcid.org/0000-0002-8370-6353
Helge EwersFaculty of Biology, Chemistry, Pharmacy, Freie Universität Berlin, Berlin, Germany.
Volker HauckeLeibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Germany. haucke@fmp-berlin.de.ORCID http://orcid.org/0000-0003-3119-6993
Michael KraussLeibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Germany. krauss@fmp-berlin.de.ORCID http://orcid.org/0000-0003-1010-9723

Funding

Deutsche Forschungsgemeinschaft (German Research Foundation) CRC 958Deutsche Forschungsgemeinschaft (German Research Foundation) TRR 186
6 · The paper itself

Abstract

Cytokinesis critically depends on phosphatidylinositol 4,5-bisphosphate [PI(4,5)P

Indexed as

CytokinesisPhosphatidylinositol 4,5-DiphosphateSeptinsContractile ProteinsHeLa CellsHumansMicrofilament ProteinsMicrotubulesProtein IsoformsanillinANLN protein, humanContractile ProteinsMicrofilament ProteinsPhosphatidylinositol 4,5-DiphosphateProtein IsoformsSeptins

Identifiers

PMID41654539
PMCPMC12886786

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.