ArticleBiology of sex differences2026
Sex-related difference of subcortical gray matter volume associated with crystallized intelligence in young adults with obesity.
Article in Biology of sex differences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Identification of critical brain regions for young adults with obesity and their relationships with impulsivity using machine learning based on neuroanatomical features.International journal of obesity (2005) · 2026Article
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8 authors.
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Abstract
backgroundOverwhelming evidence shows that obesity is associated with brain structural alterations in young adults. However, the specific sex related changes in obesity and their associated with crystallized intelligence still remained unclear.
methodsIn this study, 243 young adults with obesity and matched 243 lean individuals were enrolled from the Human Connectome Project Release S1200 dataset. Surface-based morphometry approach was adopted to investigate altered brain structures and related sex difference in young adults with obesity with three structural indicators including cortical thickness (CT), cortical surface area (CSA), and subcortical gray matter volume (GMV).
resultsWhile in female young adults, no significant difference of GMV of right amygdala was observed between obesity and lean groups, in male young adults, obesity group exhibited significantly higher GVM of right amygdala than lean group. Then, obesity male young adults showed significant correlation between GMV of right amygdala and crystallized intelligence, and such significant correlation was not found in obesity female young adults.
conclusionsObesity male young adults showed significantly higher GMV of right amygdala than lean male young adults, which was further associated with crystallized intelligence. Such findings were not observed in obesity female young adults. These findings suggested that the sex difference of adverse effect of obesity may be associated with the alterations of GMV of right amygdala.
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