Evidence map›Paper›PMID 41657713›Full record

ReviewThe Journal of innovations in cardiac rhythm management2026

Pathogenesis of Oxidative Stress Biomarkers in Atrial Fibrillation: A Narrative Review.

Hira Naveed, Aqib Ishaque, Atif Nadeem, Aneeza Waris Hussain Rathore, Sadia Akhtar, Sara Haroon, Saira Rafaqat

Abstract readReview
In one paragraph

Review in The Journal of innovations in cardiac rhythm management, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hira NaveedDepartment of Cardiology, Army Cardiac Hospital/CMH Lahore Medical College, Lahore, Pakistan.
Aqib IshaqueDepartment of Cardiology, Army Cardiac Hospital/CMH Lahore Medical College, Lahore, Pakistan.
Atif NadeemDepartment of Cardiology, Army Cardiac Hospital/CMH Lahore Medical College, Lahore, Pakistan.
Aneeza Waris Hussain RathoreDepartment of Cardiology, Army Cardiac Hospital/CMH Lahore Medical College, Lahore, Pakistan.
Sadia AkhtarDepartment of Zoology, Lahore College for Women University, Lahore, Pakistan.
Sara HaroonBachelor's Science in Nursing, Aligarh College of Nursing, Lahore, Pakistan.
Saira RafaqatDepartment of Cardiology, Army Cardiac Hospital/CMH Lahore Medical College, Lahore, Pakistan.ORCID https://orcid.org/0000-0001-7177-5602

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atrial fibrillation (AF) is the most prevalent cardiac arrhythmia. Although its pathogenesis remains incompletely elucidated, accumulating evidence implicates oxidative stress (OS) as a key contributor to the development of the arrhythmogenic substrate. OS may facilitate atrial remodeling through modulation of calcium-handling proteins and ion channel function, potentially promoting the initiation and maintenance of AF. This article summarizes the role of OS biomarkers such as 8-hydroxydeoxyguanosine (8-OHdG), glutathione peroxidase (GPx), advanced glycation end-products (AGEs), superoxide dismutase (SOD), malondialdehyde (MDA), isoprostanes (IsoPs), derivatives of reactive oxidative metabolites that oxidize reduced glutathione (E

Indexed as

Atrial fibrillationbiomarkersoxidative stresspathogenesis

Identifiers

PMID41657713
PMCPMC12880196

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.