Evidence map›Paper›PMID 41658062›Full record

ArticleACS omega2026

Synthesis and Biological Evaluation of Tetrahydroisoquinoline Derivatives as Trypanocidal Agents.

João Paulo de Moura Lopes, Gabriel Vitor de Lima Marques, Lucas Abreu Diniz, Viviane Côrrea Santos, Daniela de Melo Resende, Silvane Maria Fonseca Murta, Markus Kohlhoff, Vinícius Gonçalves Maltarollo, Rafaela Salgado Ferreira, Renata Barbosa Oliveira

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

João Paulo de Moura LopesDepartamento de Produtos Farmacêuticos, Universidade Federal de Minas Gerais, Belo Horizonte 31270901, Brazil.
Gabriel Vitor de Lima MarquesDepartamento de Produtos Farmacêuticos, Universidade Federal de Minas Gerais, Belo Horizonte 31270901, Brazil.ORCID https://orcid.org/0000-0002-7558-5555
Lucas Abreu DinizDepartamento de Bioquímica e Imunologia, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil.
Viviane Côrrea SantosDepartamento de Bioquímica e Imunologia, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil.
Daniela de Melo ResendeInstituto René RachouFIOCRUZ Minas, Belo Horizonte 30190002, Brazil.
Silvane Maria Fonseca MurtaInstituto René RachouFIOCRUZ Minas, Belo Horizonte 30190002, Brazil.
Markus KohlhoffInstituto René RachouFIOCRUZ Minas, Belo Horizonte 30190002, Brazil.
Vinícius Gonçalves MaltarolloDepartamento de Produtos Farmacêuticos, Universidade Federal de Minas Gerais, Belo Horizonte 31270901, Brazil.ORCID https://orcid.org/0000-0001-9675-5907
Rafaela Salgado FerreiraDepartamento de Bioquímica e Imunologia, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil.ORCID https://orcid.org/0000-0003-3324-0601
Renata Barbosa OliveiraDepartamento de Produtos Farmacêuticos, Universidade Federal de Minas Gerais, Belo Horizonte 31270901, Brazil.ORCID https://orcid.org/0000-0001-5884-2567

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

American trypanosomiasis is a parasitic illness of major public health relevance, resulting from infection with the protozoan

Identifiers

PMID41658062
PMCPMC12878744

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.