Evidence map›Paper›PMID 41658103›Full record

ArticleACS omega2026

Decoding C‑SH2 Domain/Peptide Interactions in SH2 Domain-Containing Tyrosine Phosphatase 2: A Molecular Framework for Rational Inhibitor Design.

Chiara Innamorati, Layla Bruno, Paolo Calligari, Gianfranco Bocchinfuso, Lorenzo Stella

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chiara InnamoratiDepartment of Chemical Sciences and Technologies, University of Rome Tor Vergata, Rome 00133, Italy.ORCID https://orcid.org/0009-0001-5813-9983
Layla BrunoDepartment of Chemical Sciences and Technologies, University of Rome Tor Vergata, Rome 00133, Italy.
Paolo CalligariDepartment of Chemical Sciences and Technologies, University of Rome Tor Vergata, Rome 00133, Italy.
Gianfranco BocchinfusoDepartment of Chemical Sciences and Technologies, University of Rome Tor Vergata, Rome 00133, Italy.ORCID https://orcid.org/0000-0002-5556-7691
Lorenzo StellaDepartment of Chemical Sciences and Technologies, University of Rome Tor Vergata, Rome 00133, Italy.ORCID https://orcid.org/0000-0002-5489-7381

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SH2 domain-containing tyrosine phosphatase 2 (SHP2), encoded by

Identifiers

PMID41658103
PMCPMC12878756

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.