ArticleCureus2026
Effect of HbA1c and Inflammatory Hematological Markers on Postoperative Outcomes in Diabetic Patients Undergoing Major Abdominal Surgery.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Diabetic patients undergoing major abdominal surgery are at increased risk of postoperative complications due to chronic hyperglycemia and altered inflammatory responses. Glycated hemoglobin (HbA1c) reflects long-term glycemic control, while complete blood count-derived inflammatory markers provide insight into systemic inflammation. This study evaluated the association of HbA1c and inflammatory hematological markers with postoperative outcomes in diabetic patients undergoing major abdominal surgery. Methods This prospective observational cohort study was conducted at Nawaz Sharif Medical College and Aziz Bhatti Shaheed Teaching Hospital, Gujrat, Pakistan, over a 12-month period from February 2024 to January 2025. Adult diabetic patients undergoing elective or emergency major abdominal surgery were enrolled using consecutive sampling. Preoperative HbA1c and inflammatory hematological parameters, including neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and lymphocyte-to-monocyte ratio (LMR), were assessed. Postoperative complications occurring during hospitalization or within 30 days were recorded. Multivariable logistic regression was performed to identify independent predictors of postoperative complications. Results A total of 205 patients were included in the final analysis. The mean age was 58.6 ± 9.8 years, and 57.6% were male patients. Overall, 77 patients (37.6%) developed postoperative complications. Patients with complications had significantly higher mean HbA1c levels compared with those without complications (8.8 ± 1.3% vs. 7.6 ± 1.2%, p < 0.001). Inflammatory markers, including total leukocyte count, neutrophil count, NLR, and PLR, were significantly elevated, whereas LMR was significantly lower in the complication group (all p < 0.001). On multivariable analysis, HbA1c (adjusted OR 1.42, 95% CI 1.18-1.72), NLR (adjusted OR 1.31, 95% CI 1.18-1.46), and PLR (adjusted OR 1.08, 95% CI 1.03-1.14) were independently associated with postoperative complications. Conclusion Elevated HbA1c and inflammatory hematological markers are independently associated with adverse postoperative outcomes in diabetic patients undergoing major abdominal surgery. These readily available parameters may aid in preoperative risk stratification and perioperative optimization.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.