Evidence map›Paper›PMID 41659347›Full record

ArticleFrontiers in molecular biosciences2025

Investigating circulating expression profile for

Marwa A Dahpy, Marwa K Khairallah, Rania Naguib, Mona A Khalil, Salwa Seif Eldin, Marwa A Sabet, Amira A Kamel

Abstract read
In one paragraph

Article in Frontiers in molecular biosciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marwa A DahpyDepartment of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Assiut University, Assiut, Egypt.
Marwa K KhairallahDepartment of Internal Medicine, Faculty of Medicine, Assiut University, Assiut, Egypt.
Rania NaguibDepartment of Internal Medicine, College of Medicine, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
Mona A KhalilDepartment of Biochemistry and Molecular Biology, Faculty of Medicine, Al-Azhar, University, Cairo, Egypt.
Salwa Seif EldinDepartment of Basic Medical Sciences, College of Medicine, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia.
Marwa A SabetDepartment of Microbiology and Immunology, Faculty of Pharmacy, Sphinx University, New-Assiut, Egypt.
Amira A KamelDepartment of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Assiut University, Assiut, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aim: Chronic kidney disease (CKD) incorporates a variety of progressive kidney function declines, ranging from mild impairment to end-stage renal disease (ESRD). As a global public health problem, early detection and monitoring remain critical for improving patient outcomes. This study aimed to evaluate the potential diagnostic significance and interrelationships of serum sclerostin, Methods: A total of 150 participants were enrolled in this present case-control study: 50 hemodialysis patients, 50 CKD patients, and 50 healthy controls. Circulating serum sclerostin levels were measured using ELISA. Real-time quantitative PCR (RT-qPCR) was used to measure the circulating levels of lncRNAs ( Results: Both the CKD and hemodialysis groups displayed significantly elevated levels of all studied biomarkers compared with controls. However, the highest levels of sclerostin, lncRNAs ( Conclusion: Serum sclerostin, lncRNAs (

Indexed as

chronic kidney diseasehemodialysislncRNA H19LncRNAMEG3lncRNA MIATmiR-135amiR-29aquantitative polymerase chain reaction

Identifiers

PMID41659347
PMCPMC12875916

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.