Evidence map›Paper›PMID 41659521›Full record

ArticlebioRxiv : the preprint server for biology2026

Ziyu Zhou, Ka Lam Nguyen, Sijie Chen, Yuexi Wang, Min Li, David M Bianchi, Weihao Ge, Shanny Hsuan Kuo, Salwa Gharieb, Emily Tung and 9 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Ziyu ZhouDepartment of Comparative Biosciences, University of Illinois Urbana-Champaign, Urbana, Illinois.
Ka Lam NguyenDepartment of Comparative Biosciences, University of Illinois Urbana-Champaign, Urbana, Illinois.
Sijie ChenDepartment of Comparative Biosciences, University of Illinois Urbana-Champaign, Urbana, Illinois.
Yuexi WangDepartment of Comparative Biosciences, University of Illinois Urbana-Champaign, Urbana, Illinois.
Min LiDepartment of Comparative Biosciences, University of Illinois Urbana-Champaign, Urbana, Illinois.
David M BianchiNational Center for Supercomputing Applications, University of Illinois Urbana-Champaign, Urbana, Illinois.ORCID 0000-0003-4674-194X
Weihao GeNational Center for Supercomputing Applications, University of Illinois Urbana-Champaign, Urbana, Illinois.ORCID 0000-0001-5306-9798
Shanny Hsuan KuoDepartment of Pathobiology, University of Illinois Urbana-Champaign, Urbana, Illinois.
Salwa GhariebDepartment of Comparative Biosciences, University of Illinois Urbana-Champaign, Urbana, Illinois.
Emily TungDepartment of Comparative Biosciences, University of Illinois Urbana-Champaign, Urbana, Illinois.
Ronak ParmarDepartment of Comparative Biosciences, University of Illinois Urbana-Champaign, Urbana, Illinois.
Jie JiDepartment of Comparative Biosciences, University of Illinois Urbana-Champaign, Urbana, Illinois.
Rohit KhoranaDepartment of Comparative Biosciences, University of Illinois Urbana-Champaign, Urbana, Illinois.
Ahmed HettaDepartment of Animal Sciences, University of Illinois Urbana-Champaign, Urbana, Illinois.
Isaac CannDepartment of Animal Sciences, University of Illinois Urbana-Champaign, Urbana, Illinois.ORCID 0000-0003-0539-0119
Roderick I MackieDepartment of Animal Sciences, University of Illinois Urbana-Champaign, Urbana, Illinois.ORCID 0000-0002-4767-9300
Gee W LauDepartment of Pathobiology, University of Illinois Urbana-Champaign, Urbana, Illinois.ORCID 0000-0002-7962-3950
Jing YangDepartment of Comparative Biosciences, University of Illinois Urbana-Champaign, Urbana, Illinois.ORCID 0009-0009-6266-0614
Wenyan MeiDepartment of Comparative Biosciences, University of Illinois Urbana-Champaign, Urbana, Illinois.ORCID 0000-0001-5270-7727

Funding

Maternal control of germline developmentR35GM131810 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI Jing Yang · 2019 to 2026
$3.2M
Mechanistic studies to develop a polysaccharide degradation signature (PDS) and its application in improving host healthR01GM140306 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI CANN, ISAAC, MEI, WENYAN · 2020 to 2023
$2.2M
Cytoplasmic remodeling during the vertebrate oocyte-to-embryo transitionR01ES036194 · NIEHS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI Jodi A. Flaws, Wenyan Mei · 2025 to 2026
$1.2M
NIEHS NIH HHS R01 ES036194NIGMS NIH HHS R01 GM140306NIGMS NIH HHS R35 GM131810
6 · The paper itself

Abstract

Insufficient dietary fiber intake is strongly associated with gut microbiome dysfunction and an increased risk of noncommunicable diseases. Synergistic synbiotics, which pair defined microbial strains with their preferred carbohydrate substrates, offer a promising strategy to restore these functions. However, the rational design of such interventions remains challenging because of insufficient understanding of microbial fiber-degrading capacities and the host-relevant bioactivities of fermentation-derived metabolites. Here, we identify human colonic commensal

Identifiers

PMID41659521
PMCPMC12873859

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.