Evidence map›Paper›PMID 41659564›Full record

ArticlebioRxiv : the preprint server for biology2026

Altered immune and treatment response gene expression signatures among poverty-exposed children with B-ALL.

Amy Guillaumet-Adkins, Noori Sotudeh, Sayalee Potdar, Tushara Vijaykumar, Monica Nair, Valeriya Dimitrova, Julia Frede, Yana Pikman, Marian Harris, Andrew E Place and 4 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Amy Guillaumet-AdkinsPediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Noori SotudehPediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Sayalee PotdarPediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Tushara VijaykumarMedical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Monica NairMedical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Valeriya DimitrovaPediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Julia FredeMedical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Yana PikmanPediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Marian HarrisHarvard Medical School, Boston, MA, USA.
Andrew E PlacePediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Lewis B SilvermanPediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Jens G LohrBroad Institute of Harvard and MIT, Cambridge, MA, USA.
Kira BonaPediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Birgit KnoechelPediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.

Funding

VectorP30CA006516 · NCI · DANA-FARBER CANCER INSTITUTE · PI Irene M. Ghobrial · 1985 to 2026
$330.6M
Mechanisms of immune evasion in T-cell acute lymphoblastic leukemia and its therapeutic implicationsR01CA249185 · NCI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI KNOECHEL, BIRGIT · 2021 to 2025
$1.9M
NCI NIH HHS P30 CA006516NCI NIH HHS R01 CA249185
6 · The paper itself

Abstract

Children diagnosed with cancer typically receive standardized treatment regimens. Despite highly protocolized care, children living in poverty experience a greater risk of cancer relapse and higher mortality compared to their more affluent peers.

Identifiers

PMID41659564
PMCPMC12873972

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.