ArticleFrontiers in fungal biology2026
Free radical inhibition and total phenolic content in
Article in Frontiers in fungal biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Given the growing recognition of Methods: This study investigated the effects of various cultivation parameters on biomass accumulation, total phenolic content (TPC), and free radical scavenging activity, assessed using the Folin-Ciocalteu and DPPH assays respectively. Results and Discussion: Among solvents tested, methanol and 70% ethanol were most effective for phenolic extraction, yielding 20.54±0.11 and 19.39±0.14mg GAE/g, respectively, while some solvents demonstrated strong DPPH inhibition (≥90%). A cultivation at 25°C supported optimal biomass accumulation (5.23±0.10g/L), phenolic compound total yield (101.10mg GAE/L), and antioxidant activity (91.66±0.40%). Static cultivation conditions promoted surface mycelial growth and resulted in the highest biomass yield (5.28±0.15g/L), strong DPPH inhibition (≥90%), and phenolic synthesis (101.75mg GAE/L). Among carbon sources, maltose favored biomass formation, whereas xylose led to the highest DPPH inhibition (89.68±0.91%) and TPC (16.08±0.06mg GAE/g; total yield: 15.92mg GAE/L). Of the nitrogen sources evaluated, ammonium sulfate supported the greatest biomass accumulation (2.64±0.21g/L), while ammonium nitrate enhanced antioxidant activity (80.54±3.10%). Although urea produced the highest TPC per gram of dry biomass (11.32±0.05mg GAE/g), ammonium sulfate resulted in the highest phenolic total yield (18.43mg GAE/L). An initial medium pH of 6.0 was identified as optimal for maximizing biomass growth, phenolic compound production, and antioxidant capacity. The cultivation parameters were ranked in order of influence as: temperature > duration of static cultivation > pH > duration of agitation > carbon source > nitrogen source. These findings provide a foundation for the targeted optimization of cultivation conditions to enhance biomass production, phenolic compound accumulation, and antioxidant activity in
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.