Evidence mapPaperPMID 41663329Full record

Trial reportPhysiological reports2026

Exercise FITT-V in pregnancy with obesity: Preliminary findings for infant adiposity and intergenerational obesity risk.

Alex Claiborne, Filip Jevtovic, Ericka M Biagioni, Lindsey Rossa, Caitlyn Ollmann, Donghai Zheng, Cody Strom, Breanna Wisseman, Samantha McDonald, Edward Newton and 6 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Physiological reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Alex ClaiborneDepartment of Kinesiology, Nutrition, and Health, Miami University, Oxford, Ohio, USA.ORCID https://orcid.org/0000-0001-7427-3851
Filip JevtovicDepartment of Translational Neuroscience, Division of Molecular Medicine, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA.
Ericka M BiagioniDepartment of Kinesiology, East Carolina University (ECU), Greenville, North Carolina, USA.
Lindsey RossaDepartment of Kinesiology, East Carolina University (ECU), Greenville, North Carolina, USA.
Caitlyn OllmannDepartment of Biomedical Sciences, Quinnipiac University, Hamden, Connecticut, USA.
Donghai ZhengDepartment of Kinesiology, East Carolina University (ECU), Greenville, North Carolina, USA.
Cody StromDepartment of Human Performance, Minnesota State University, Mankato, Minnesota, USA.
Breanna WissemanDepartment of Kinesiology, University of Rhode Island, Kingston, Rhode Island, USA.
Samantha McDonaldSchool of Kinesiology and Recreation, Illinois State University, Normal, Illinois, USA.
Edward NewtonDepartment of Obstetrics & Gynecology, ECU, Greenville, North Carolina, USA.
Steven MouroDepartment of Obstetrics & Gynecology, ECU, Greenville, North Carolina, USA.
James DeVenteDepartment of Obstetrics & Gynecology, ECU, Greenville, North Carolina, USA.
George A KelleySchool of Public and Population Health, Boise State University, Boise, Idaho, USA.
Joseph A HoumardDepartment of Kinesiology, East Carolina University (ECU), Greenville, North Carolina, USA.ORCID https://orcid.org/0000-0003-3682-5410
Nicholas T BroskeyDepartment of Kinesiology, East Carolina University (ECU), Greenville, North Carolina, USA.
Linda E MayDepartment of Kinesiology, East Carolina University (ECU), Greenville, North Carolina, USA.ORCID https://orcid.org/0000-0002-8231-2280

Funding

Effect of exercise modality during pregnancy on childhood obesity riskR01DK129480 · EAST CAROLINA UNIVERSITY · 2025 to 2025
$662k
Effect of Maternal Exercise in Women with Obesity on Offspring Mesenchymal Stem Cell MetabolismR01DK137945 · EAST CAROLINA UNIVERSITY · 2025 to 2025
$473k
American Heart Association (AHA) 15GRNT24470029American Heart Association (AHA) 18IPA34150006HHS | National Institutes of Health (NIH) 5R01DK129480-01HHS | National Institutes of Health (NIH) R01DK137945NIDDK NIH HHS R01 DK129480NIDDK NIH HHS R01 DK137945Thrasher Research Fund (TRF) 02154
6 · The paper itself

Abstract

Prenatal exercise decreases offspring adiposity, but it is uncertain whether this relationship is present in offspring exposed to obesity in utero. We aimed to determine whether exercise during pregnancy reduces infant cellular and whole-body adiposity in offspring born to women with obesity. This is a sub-analysis of a randomized controlled trial, where women were randomized to supervised exercise or control for ~24 weeks during pregnancy. Exercise FITT-V metrics (frequency, intensity, time, type, and volume) were collected. Infant mesenchymal stem cells (MSCs) (healthy weight [n = 16], obesity [n = 21]) were adipogenically differentiated and stained for lipid content. Infant body composition was measured at 1 month of age via skinfold. Among women randomized to control, maternal BMI influenced infant adiposity; infants exposed to obesity had higher body fat percentage (p = 0.02). Birthweight was negatively correlated with infant body fat; offspring with lower birthweight had higher body fat (R

Indexed as

AdiposityExerciseObesityPregnancy in ObesityPrenatal Exposure Delayed EffectsAdultBirth WeightFemaleHumansInfantInfant, NewbornPregnancyadipositybirthweightdose responseobesityprenatal exercise

Identifiers

PMID41663329
PMCPMC12885935

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.