Evidence map›Paper›PMID 41663420›Full record

ArticleNPJ science of food2026

Effects of Lactiplantibacillus plantarum on moderate dyslipidemia before medication involving gut microbiota and host genetics.

Guoqing Ma, Yunfeng Li, Chen He, Junqi Li, Jiawen Xie, Maab Mohammed Alballa, Kun Xu, Xinran Feng, Juan He, Kaizhen Jia and 13 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NPJ science of food, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Guoqing Ma *Department of Epidemiology and Biostatistics, School of Public Health, Global Health Institute, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Yunfeng Li *Department of Epidemiology and Biostatistics, School of Public Health, Global Health Institute, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Chen HeDepartment of Epidemiology and Biostatistics, School of Public Health, Global Health Institute, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Junqi LiDepartment of Epidemiology and Biostatistics, School of Public Health, Global Health Institute, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Jiawen XieDepartment of Epidemiology and Biostatistics, School of Public Health, Global Health Institute, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Maab Mohammed AlballaDepartment of Epidemiology and Biostatistics, School of Public Health, Global Health Institute, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Kun XuDepartment of Epidemiology and Biostatistics, School of Public Health, Global Health Institute, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Xinran FengDepartment of Epidemiology and Biostatistics, School of Public Health, Global Health Institute, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Juan HeDepartment of Epidemiology and Biostatistics, School of Public Health, Global Health Institute, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Kaizhen JiaDepartment of Epidemiology and Biostatistics, School of Public Health, Global Health Institute, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Yifei HeDepartment of Epidemiology and Biostatistics, School of Public Health, Global Health Institute, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Wei LiDepartment of Epidemiology and Biostatistics, School of Public Health, Global Health Institute, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Fangyao ChenDepartment of Epidemiology and Biostatistics, School of Public Health, Global Health Institute, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Baibing MiDepartment of Epidemiology and Biostatistics, School of Public Health, Global Health Institute, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Jiaomei YangDepartment of Epidemiology and Biostatistics, School of Public Health, Global Health Institute, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Hang YuDepartment of Cardiovascular Medicine, The First Affiliated Hospital, Xi'an Jiaotong University, Xi'an, China.
Xia LiaoDepartment of Nutrition, The First Affiliated Hospital, Xi'an Jiaotong University, Xi'an, China.
Baoming ZhangCollege of Stomatology, Xi'an Jiaotong University, Xi'an, China.
Nan YangHealth Management Department, Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Quanfeng DongMicrobiome Research and Application Center, BYHEALTH Institute of Nutrition & Health, Guangzhou, China.
Qian WangHealth Management Department, Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China. wangqian0707@xjtu.edu.cn.
Xiaolei ZeMicrobiome Research and Application Center, BYHEALTH Institute of Nutrition & Health, Guangzhou, China. zexl@by-health.com.
Xin LiuDepartment of Epidemiology and Biostatistics, School of Public Health, Global Health Institute, Xi'an Jiaotong University Health Science Center, Xi'an, China. xinliu@xjtu.edu.cn.

Funding

BYHEALTH Nutrition and Health Research Foundation TY202104001National Natural Science Foundation of China 82173504Science and Technology Resources Open Sharing Platform of the Shaanxi Province 2023-CX-PT-47Xi'an Jiaotong University DW080038K0000004
6 · The paper itself

Abstract

In this 12-week trial, 136 participants with moderately dyslipidemia were randomly assigned to receive Lactiplantibacillus plantarum (LP) or placebo. In the intention-to-treat analysis, the group-by-time interaction did not reach statistical significance. However, in per-protocol set (adherence ≥85% and no antibiotic use), LP supplementation reduced low-density lipoprotein cholesterol (LDL-C) (-0.118 mmol/L) and total cholesterol (TC) (-0.163 mmol/L), compared with the placebo (both P

Identifiers

PMID41663420
PMCPMC12996313

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.