Evidence mapPaperPMID 41663540Full record

SynthesisSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2026

Effects of exercise on people living with advanced lung cancer: a systematic review and meta-analysis.

Eisuke Ochi, Takuya Fukushima, Utae Katsushima, Takashi Yamashita, Jiro Nakano

Abstract readSystematic ReviewMeta-AnalysisReview
PubMed Publisher
In one paragraph

Synthesis in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Eisuke Ochi *Faculty of Bioscience and Applied Chemistry, Hosei University, Tokyo, 184-8584, Japan. ochi@hosei.ac.jp.ORCID http://orcid.org/0000-0002-2497-0250
Takuya Fukushima *Faculty of Rehabilitation, Kansai Medical University, Osaka, 573-1136, Japan.ORCID http://orcid.org/0000-0001-7075-9264
Utae KatsushimaDepartment of Thoracic Oncology, Kansai Medical University, Osaka, 573-1191, Japan.
Takashi YamashitaGraduate School of Sports and Health Studies, Hosei University, Tokyo, 194-0298, Japan.
Jiro NakanoFaculty of Rehabilitation, Kansai Medical University, Osaka, 573-1136, Japan.ORCID http://orcid.org/0000-0003-1327-3211

Funding

Japan Society for the Promotion of Science 22K17603
6 · The paper itself

Abstract

purposeExercise has the potential to improve and maintain physical function, alleviate symptoms, improve quality of life, and influence prognosis in patients with advanced lung cancer. This systematic review and meta-analysis of randomized controlled trials (RCTs) primarily examined the impact of exercise on physical function, with a focus on cardiorespiratory fitness.

methodsA systematic search of PubMed, Cochrane Library, Web of Science, and CINAHL was conducted from inception to June 28, 2024. Eligible RCTs examined exercise interventions in patients with advanced lung cancer, evaluating physical function, symptoms, quality of life, and prognosis. Subgroup analyses were performed based on measurement sites and items. Standardized mean differences (SMDs) with 95% confidence intervals (CIs) were calculated for quantitative outcomes, and a random-effects model was used for data pooling.

resultsNine RCTs (from 4,262 retrieved articles) were included in the meta-analysis. The results indicated that patients who participated in exercise interventions had greater improvements in VO

conclusionsWe conclude that exercise plays a crucial role in improving cardiorespiratory fitness, muscle strength, quality of life, and fatigue in patients with advanced lung cancer, highlighting the importance of incorporating exercise into their cancer care. However, future studies, including head-to-head comparative trials, are required to clarify the effects of different exercise types and their impact on prognosis. PROSPERO Registration Number: CRD42024575482.

Indexed as

ExerciseExercise TherapyLung NeoplasmsQuality of LifeCardiorespiratory FitnessFatigueHumansMuscle StrengthPrognosisRandomized Controlled Trials as TopicCardiorespiratory fitnessExerciseMeta-analysisOncologyPhysical activityQuality of lifeSystematic review

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.