Evidence map›Paper›PMID 41663810›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2026

mPEG-functionalized polyadipate triblock copolymers as promising nanocarriers for the controlled delivery of therapeutic agents in breast cancer treatment.

Nazan Gökşen Tosun, Seçil Erden Tayhan, İsa Gökçe, Cemil Alkan

Abstract read
In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nazan Gökşen TosunDepartment of Medical Services and Techniques, Tokat Vocational School of Health Sciences, Tokat Gaziosmanpaşa University, Tokat, Turkey.
Seçil Erden TayhanDepartment of Pharmaceutical Biotechnology, Pharmacy Faculty, Tokat Gaziosmanpaşa University, Tokat, Turkey.
İsa GökçeDepartment of Biochemistry, Pharmacy Faculty, Tokat Gaziosmanpaşa University, Tokat, Turkey. isa.gokce@gop.edu.tr.
Cemil AlkanDepartment of Chemistry, Science and Letters Faculty, Tokat Gaziosmanpaşa University, Tokat, Turkey. cemil.alkan@gop.edu.tr.

Funding

Tokat Gaziosmanpaşa University Scientific Foundation of Scientific Research Projects 2020/66
6 · The paper itself

Abstract

The increasing incidence of breast cancer is leading researchers to investigate new treatment approaches. Targeted therapy approaches are particularly attractive because they minimize the detrimental effects of therapeutic agents on healthy tissues and cells by focusing on tumor sites. This study focuses on synthesizing mPEG-modified triblock copolymers as carrier materials for drug delivery applications, enabling the efficient encapsulation of DOX, and evaluating the cytotoxic effects of the resulting nanocarriers on breast cancer cell lines. In this study, mPEG-poly(butylene adipate)-mPEG and mPEG-poly(ethylene adipate)-mPEG triblock copolymers were synthesized by a step-growth polycondensation polymerization method. Firstly, poly(butylene adipate) (pBAd) and poly(ethylene adipate) (pEAd) were synthesized to form the body of the triblock copolymer, and their chemical structures were characterized using Fourier transform infrared (FT-IR) and

Indexed as

Antibiotics, AntineoplasticBreast NeoplasmsDoxorubicinDrug CarriersNanoparticlesPolyestersPolyethylene GlycolsCell Line, TumorCell SurvivalDelayed-Action PreparationsFemaleHumansMCF-7 CellsMDA-MB-231 CellsAntibiotics, AntineoplasticDelayed-Action PreparationsDoxorubicinDrug Carriersmonomethoxypolyethylene glycolPolyestersPolyethylene GlycolsBreast cancerDoxorubicinNanocarriersPEGylationPolyadipateTriblock copolymer

Identifiers

PMID41663810
PMCPMC13152887

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.