Evidence map›Paper›PMID 41664042›Full record

ArticleMolecular cancer2026

STING-Activating nanoplatforms for image-guided sonodynamic cancer therapy.

Lingpu Zhang, Delong Huang, Jia Li, Linzhen Mo, Tian Qin, Bowen Xing, Bing Xiao, Chun Xu, Haihua Xiao, Leli Zeng and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lingpu ZhangBeijing National Laboratory for Molecular Science, State Key Laboratory of Polymer Physics and Chemistry, Institute of Chemistry, Chinese Academy of Science, Beijing, 100190, China.
Delong HuangWuhan research institute of posts and telecommunications, Wuhan, 430074, China.
Jia LiDigestive Diseases Center, Guangdong Provincial Key Laboratory of Digestive Cancer Research, Precision Medicine Center, The Biobank, Scientific Research Center, The Seventh Affiliated Hospital of Sun Yat-Sen University, Shen zhen, Guangdong, China.
Linzhen MoDigestive Diseases Center, Guangdong Provincial Key Laboratory of Digestive Cancer Research, Precision Medicine Center, The Biobank, Scientific Research Center, The Seventh Affiliated Hospital of Sun Yat-Sen University, Shen zhen, Guangdong, China.
Tian QinDigestive Diseases Center, Guangdong Provincial Key Laboratory of Digestive Cancer Research, Precision Medicine Center, The Biobank, Scientific Research Center, The Seventh Affiliated Hospital of Sun Yat-Sen University, Shen zhen, Guangdong, China.
Bowen XingCollege of Life Science and Technology, Beijing University of Chemical Technology, Beijing, 100029, China.
Bing XiaoDepartment of Nuclear Medicine, Peking University People's Hospital, Beijing, 100044, China.
Chun XuSydney Dental School, Faculty of Medicine and Health, Charles Perkins Centre, The University of Sydney, Camperdown, NSW, 2006, Australia.
Haihua XiaoBeijing National Laboratory for Molecular Science, State Key Laboratory of Polymer Physics and Chemistry, Institute of Chemistry, Chinese Academy of Science, Beijing, 100190, China.
Leli ZengBeijing National Laboratory for Molecular Science, State Key Laboratory of Polymer Physics and Chemistry, Institute of Chemistry, Chinese Academy of Science, Beijing, 100190, China. zenglli6@mail.sysu.edu.cn.
Kun ShangDepartment of Nuclear Medicine, Peking University People's Hospital, Beijing, 100044, China. shkn@bjmu.edu.cn.

Funding

Postdoctoral Fellowship Program of CPSF GZB20230773Shenzhen Medical Research Fund A2403045the National Natural Science Foundation of China 22305272the National Natural Science Foundation of China 22307151the National Natural Science Foundation of China U24A202246
6 · The paper itself

Abstract

Tumor precision treatment still faces the challenge of being unable to achieve real-time monitoring. The rapid advancements in nanomedicine within the biomedical sector have highlighted the potential of integrated nano-platforms for tumor diagnosis and treatment. Herein, we create a multimodal diagnostic nanodrug, ⁹⁹

Indexed as

Breast NeoplasmsMembrane ProteinsNanoparticlesNeoplasmsUltrasonic TherapyAnimalsCell Line, TumorcGAS-STING Signaling PathwayFemaleHumansMiceReactive Oxygen SpeciesSTING ProteinMembrane ProteinsReactive Oxygen SpeciesSTING1 protein, humanSTING ProteincGAS-STINGNuclear imagingPolymer nanocarriersSonodynamic therapyTheranostic nanodrug

Identifiers

PMID41664042
PMCPMC12983522

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.