Evidence map›Paper›PMID 41664284›Full record

SynthesisJournal of occupational and environmental medicine2026

The Respiratory Effects of Jet Fuel Exposure: A Fit-for-Purpose Systematic Literature Review and Evidence Synthesis.

Emma C Bowers, Elizabeth M Martin, Meredith Clemons, Anna Kolanowski, Anastasia N Freedman, Hannah M Starnes, Justin G Bergeron, Janielle Vidal, Manasi Kotulkar, Rachel P Renda and 7 more

Abstract readSystematic Review
In one paragraph

Synthesis in Journal of occupational and environmental medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Emma C BowersFrom ICF, Reston, Virginia (E.C.B., E.M.M., M.C., A.K., A.N.F., H.M.S., J.V., M.K., R.P.R., S.J.G., S.J.S., S.E.E., C.E.H.); Exposure Science Program, Health Outcomes Military Exposures, Department of Veterans Affairs, Washington, DC (J.G.B., T.D.V.H.); Airborne Hazards and Burn Pits Center of Excellence, War Related Illness and Injury Study Center, Department of Veterans Affairs, East Orange, New Jersey, (M.J.F.).ORCID 0000-0002-2009-2489
Elizabeth M MartinORCID 0000-0001-8428-7034
Anastasia N FreedmanORCID 0000-0001-6107-4642
Justin G BergeronORCID 0009-0009-2665-8277
Samantha J GoodmanORCID 0000-0003-4828-0964
Jenna L N SprowlesORCID 0000-0001-6198-8057
Terra D Vincent-HallORCID 0009-0000-4218-4010

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveJet fuel inhalation represents one of the most significant exposures among service members; however, health outcomes are unclear, and the processes linking exposures and respiratory effects are undefined.

methodsA systematic literature review of human, animal, and mechanistic studies was conducted to assess and synthesize the scientific evidence on the adverse respiratory effects of jet fuel exposure.

resultsAnimal studies provided moderate evidence that jet fuel inhalation resulted in adverse effects through cytotoxicity, tissue damage, inflammation, airway remodeling, and lung function changes, which was corroborated by mechanistic data. This was further supported by slight epidemiologic evidence that jet fuel exposure is associated with increased respiratory symptoms and disease.

conclusionsEvidence indicates that jet fuel exposure is likely to produce adverse respiratory effects, which may have important implications for exposed service members and veterans.

Indexed as

HydrocarbonsInhalation ExposureOccupational ExposureAirway RemodelingAnimalsHumansHydrocarbonsJP8 aviation fuelairway remodelingCOPDjet fuelslung permeabilitypulmonary inflammationrespiratory toxicity

Identifiers

PMID41664284
PMCPMC12928832

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.