ArticleJournal of clinical periodontology2026
Association of Edentulism With Subsequent Biological Age: A Cohort Study.
Article in Journal of clinical periodontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Minimally Invasive Implant Rehabilitation in Geriatric Patients: A Comprehensive Narrative Review of Contemporary Strategies to Avoid Extensive Bone Augmentation Procedures.Geriatrics (Basel, Switzerland) · 2026Review
- Association of Edentulism With Subsequent Biological Age: A Cohort Study.Journal of clinical periodontology · 2026Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
backgroundBiological ageing is characterised by a gradual decline in physiological functions, resulting in increased susceptibility to diseases and mortality. We investigated the relationship between edentulism and biological ageing among adults in England.
methodsData were drawn from participants in the English Longitudinal Study of Ageing who completed three consecutive biennial waves (waves 2-3-4 or 4-5-6), yielding 1889 individuals providing 2390 three-wave panel observations (mean age at baseline 68.1; men 47.7%). Edentulism was assessed in waves 3 and 5. Biological ageing was estimated using the Klemera and Doubal method, integrating multiple biomarkers assessed in waves 2, 4 and 6. Linear regression with clustered standard errors was employed to evaluate the association between edentulism and biological age in the subsequent wave (i.e., 2 years after the assessment of edentulism). Models were adjusted for pre-exposure confounders, including biological age, gender, socioeconomic status, existing health conditions and functional limitation assessed in the prior wave (i.e., 2 years before the assessment of edentulism).
resultsParticipants with edentulism exhibited a 5.8-year greater biological age than those with some remaining teeth in the subsequent waves. After adjusting for confounding variables, edentulism was associated with a 0.82-year greater biological age than those with some remaining teeth (95% confidence interval: 0.40-1.24) in the subsequent waves.
conclusionEdentulism was longitudinally associated with a greater biological age. Strategies that incorporate oral health promotion, particularly the prevention of tooth loss, may contribute to healthy ageing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.