ArticleJournal of Korean medical science2026
Quantitative Cardiac MRI in COVID-19 Vaccine-Related Versus Other Types of Myocarditis: A Korean Multicenter Study.
Article in Journal of Korean medical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundCoronavirus disease 2019 (COVID-19) vaccine-related myocarditis (C-VRM) is a potential adverse event following mRNA-based vaccination. Cardiac magnetic resonance imaging (CMR) is pivotal for diagnosing and monitoring myocarditis. This study compared quantitative CMR findings among C-VRM, COVID-19 myocarditis, and other myocarditis in the Korean population, and identified prognostic factors associated with adverse outcomes.
methodsThis retrospective multicenter study included patients diagnosed with various types of myocarditis who underwent CMR in four tertiary-care hospitals between October 2018 and January 2023. Clinical data and CMR findings, including cine, native T1, T2, extracellular volume (ECV), and late gadolinium enhancement (LGE) were analyzed. Differences in CMR parameters among myocarditis types were analyzed using linear regression. Predictors of adverse outcomes, defined as a composite of left ventricular ejection fraction (LVEF) of < 40% at follow-up and all-cause mortality, were assessed using logistic regression analysis.
resultsA total of 82 patients (mean age, 42.8 ± 19.2 years; 40 men) were included: 29 with C-VRM, 7 with COVID-19 myocarditis, and 46 with other myocarditis. C-VRM showed significantly lower native T1, T2, and ECV than other myocarditis (
conclusionIn this Korean multicenter cohort, CMR markers of myocardial injury were lower in C-VRM than in other myocarditis types, whereas prognosis was more strongly associated with injury severity than with disease subtype.
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