Evidence map›Paper›PMID 41665714›Full record

ArticleProbiotics and antimicrobial proteins2026

Pomelo Peel and Soybean Meal Fermented by Three Probiotics or in Combination with Enzymes: A Comparative Study on growth, Immunity and Intestinal Health of Larimichthys crocea.

Xi-Yue Ding, Yu-Hang Hong, Zi-Yan Liu, Hong-Ling Yang, Guo-He Cai, Pan Wang, Chuang-Zhong Zhu, Jie Su, Yun-Zhang Sun

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Probiotics and antimicrobial proteins, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xi-Yue DingState Key Laboratory of Mariculture Breeding, Fisheries college of Jimei university, Xiamen, 361021, China.
Yu-Hang HongState Key Laboratory of Mariculture Breeding, Fisheries college of Jimei university, Xiamen, 361021, China.
Zi-Yan LiuState Key Laboratory of Mariculture Breeding, Fisheries college of Jimei university, Xiamen, 361021, China.
Hong-Ling YangState Key Laboratory of Mariculture Breeding, Fisheries college of Jimei university, Xiamen, 361021, China.
Guo-He CaiState Key Laboratory of Mariculture Breeding, Fisheries college of Jimei university, Xiamen, 361021, China.
Pan WangKey Laboratory of Aquatic Functional Feed and Environmental Regulation of Fujian Province, Fujian DBN Aquatic Sci. & Tech. Co., Ltd, Zhangzhou, 363500, China.
Chuang-Zhong ZhuKey Laboratory of Aquatic Functional Feed and Environmental Regulation of Fujian Province, Fujian DBN Aquatic Sci. & Tech. Co., Ltd, Zhangzhou, 363500, China.
Jie SuFisheries Research Institute of Fujian, Xiamen, 361000, China. 23256438@qq.com.
Yun-Zhang SunState Key Laboratory of Mariculture Breeding, Fisheries college of Jimei university, Xiamen, 361021, China. jmusunyunzhang@163.com.

Funding

Basic research special fund of Fujian provincial public interest scientific research institutes 2024R1013005Science and Technology Major/Special Project of Fujian Province 2021NZ029022
6 · The paper itself

Abstract

A 56-day feeding trial was conducted to compare the effects of pomelo peel and soybean meal (SM) fermented by microorganisms alone (BFPS) or in combination with enzymes (EBFPS) on growth performance, serum biochemistry, and intestinal health of large yellow croaker (Larimichthys crocea). Large yellow croaker was randomly assigned to three groups (C, BFPS, and EBFPS) with four replicates per group and 160 fish per replicate. Results showed that BFPS and EBFPS significantly improved the growth performance and feed utilization. Fish fed BFPS- and EBFPS-containing diets exhibited reduced hepatosomatic index and serum activities of aspartate transaminase and alanine transferase, indicating superior liver health. Additionally, dietary BFPS and EBFPS increased serum lysozyme activity and immunoglobulin M concentration, while significant enhancement of serum alkaline phosphatase and acid phosphatase activities was only observed in the EBFPS group. Improvements of mid-intestinal morphology in BFPS and EBFPS groups were accompanied by reduced serum diamine oxidase activity and D-lactate content, as well as up-regulated expression of tight junction-related genes (zo-1, claudin-11, and occludin) in the mid-intestine. Interestingly, BFPS was associated with suppressed mid-intestinal inflammation and activated toll-like receptor (TLR) signaling, whereas EBFPS induced moderate inflammatory responses and down-regulated TLR signaling. The results of mid-intestinal microbiota showed that compared with C and BFPS groups, croakers fed the EBFPS diet exhibited a higher Shannon index and distinct community structures. Moreover, BFPS led to reducing mid-intestinal Brevinema but sharply increased Desulfobacterota, Lawsonia and Pseudomonas abundances, while EBFPS decreased Desulfobacterota, Lawsonia and Brevinema and increased unclassified_Bacteria. Overall, both BFPS and EBFPS positively modulated growth performance and mid-intestinal health, with distinct effects on immune responses and microbial community composition in large yellow croaker (L. crocea).

Indexed as

Animal FeedGlycine maxIntestinesPerciformesProbioticsAnimalsDietEnzymesFermentationEnzymesEnzyme-assisted microbial fermentationImmune responseIntestinal healthLarge yellow croakerMicrobial homeostasisPomelo peel

Identifiers

PMID41665714

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.