Evidence map›Paper›PMID 41665804›Full record

ArticleDiscover oncology2026

Bibliometric analysis reveals the current status and future trends of cancer associated photodynamic therapy in breast cancer.

Jinxiu Xie, Siying Chen, Shaoyu Fu, Jiayi Rao, Chenxi Wang, Yan Xiao, Kang Zou

Abstract read
PubMed Publisher
In one paragraph

Article in Discover oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jinxiu Xie *Department of Thyroid and Breast Surgery, Ji'an Central People's Hospital, Ji'an, 343000, Jiangxi, The People's Republic of China.
Siying Chen *The First Clinical Medical College, Gannan Medical University, Ganzhou, 341000, Jiangxi, The People's Republic of China.
Shaoyu FuThe First Clinical Medical College, Gannan Medical University, Ganzhou, 341000, Jiangxi, The People's Republic of China.
Jiayi RaoThe First Clinical Medical College, Gannan Medical University, Ganzhou, 341000, Jiangxi, The People's Republic of China.
Chenxi WangThe First Clinical Medical College, Gannan Medical University, Ganzhou, 341000, Jiangxi, The People's Republic of China.
Yan XiaoDepartment of Pathology, Ji'an Central People's Hospital, Ji'an, 343000, Jiangxi, The People's Republic of China.
Kang ZouDepartment of Critical Care Medicine, the First Affiliated Hospital of Gannan Medical University, Ganzhou, 341000, Jiangxi, The People's Republic of China. zoukang@gmu.edu.cn.

Funding

the General Research Topics on Teaching Reform at Gannan Medical University, China Jgkt-2024-98
6 · The paper itself

Abstract

backgroundPhotodynamic therapy (PDT) has emerged as a promising minimally invasive strategy for breast cancer, leveraging photosensitizing agents, light activation, and oxygen to generate cytotoxic effects. This bibliometric analysis explores the knowledge structure, evolutionary trends, and research frontiers within the PDT domain for breast cancer from 2000 to 2025.

methodsData were retrieved from the Web of Science Core Collection and PubMed (2000–2025). A total of 3,785 publications were analyzed using Bibliometrix, VOSviewer, and CiteSpace for co-authorship, co-citation, keyword co-occurrence, and burst detection analyses.

resultsAnnual publications grew markedly, peaking in 2025. China led in productivity and citations, while the Chinese Academy of Sciences showed the highest betweenness centrality. Biomaterials was the most influential journal, and author collaboration networks revealed limited connectivity among core researchers. Keyword evolution identified three phases: basic exploration (2000–2017), technical development (2013–2021), and the current precision immunomodulation era (2020–present), with “tumor microenvironment” and “immunogenic cell death” as dominant contemporary themes.

conclusionThis study delineates the intellectual landscape and shifting paradigms in breast cancer PDT research, underscoring a transition toward immune-focused and tumor-microenvironment–modulating strategies. Future efforts should prioritize interdisciplinary collaboration and PDT–immunotherapy combinations to advance clinical translation.

Indexed as

Bibliometric analysisBreast cancerImmunogenic cell deathPhotodynamic therapyTumor microenvironment

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.