ArticleJMIR research protocols2026
Hand and Arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE@home) for Adults With Chronic Stroke: Protocol for a Randomized Controlled Trial.
Article in JMIR research protocols, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Intensive therapies based on motor skill learning have been widely used in stroke rehabilitation for improving upper extremity abilities, demonstrating significant improvements in arm function and daily life activities. Based on the same therapeutic principles of motor skill learning, hand and arm bimanual intensive therapy including lower extremities (HABIT-ILE) was developed focusing on bimanual coordination and constant concomitant stimulation of trunk control and lower extremities. However, the implementation of such high-dosage interventions in stroke rehabilitation might face barriers due to limited accessibility and high resource requirements. Delivering HABIT-ILE therapy at home (HABIT-ILE@home) via telerehabilitation may reduce logistical barriers while maintaining efficacy. In addition, the added value of a 9-week specific follow-up program will be tested after high dosage interventions. Objective: The first randomized controlled trial (RCT1) aims to evaluate the noninferiority of a high-dosage HABIT-ILE@home program compared to its on-site counterpart. The second randomized controlled trial (RCT2) aims to test the superiority of a 9-week specific HABIT-ILE@home follow-up vs a nonspecific home program. Methods: A total of 48 adults with chronic stroke will be randomized to either HABIT-ILE@home or HABIT-ILE on-site group (RCT1, 65 hours over 2 weeks). HABIT-ILE@home will follow the same principles as HABIT-ILE on-site but will be delivered by caregivers with remote supervision by trained therapists and the use of a dedicated telerehabilitation device to facilitate intervention delivery and remote monitoring (ie, REAtouch Lite; Axinesis). All participants will then participate in a HABIT-ILE@home follow-up program or nonspecific follow-up (RCT2, 45 hours over 9 weeks). Primary outcomes will be the change in Fugl-Meyer Assessment (FMA), while secondary outcomes include feasibility and adherence questionnaires, upper and lower extremity motor function assessments, daily activities, and quality of life questionnaires. Assessments will be performed before (T0) and after (T1) the 2 weeks of high dosage intervention, followed by an assessment after the 9-week follow-up (T2). Results: Recruitment for the trial started in March 2023 and ended in March 2025, and data collection has been completed for this study. Data analysis is planned to start early 2026; we expect to submit the results for publication in spring 2026. Conclusions: This study will provide evidence on the feasibility and efficacy of delivering HABIT-ILE through a home-based telerehabilitation model for adults with chronic stroke. Demonstrating noninferiority of HABIT-ILE@home compared to on-site therapy would support wider accessibility to intensive rehabilitation while reducing logistical and human resource constraints. Additionally, showing the added benefit of a structured follow-up could emphasize the importance of continuity of care to sustain and enhance motor recovery after intensive interventions.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.