Evidence map›Paper›PMID 41667137›Full record

Trial reportEuropean heart journal2026

Computed tomography-guided vs conventional catheter ablation for ventricular tachycardia: the InEurHeart trial.

Frederic Sacher, Tobias Reichlin, Mathieu Le Bloa, Gregoire Massoulie, Xavier Waintraub, Philippe Maury, Daniel Scherr, Romain Tixier, Benoit Guy-Moyat, Josselin Duchateau and 25 more

Registry-linked trialAbstract readRandomized Controlled TrialMulticenter StudyComparative Study
In one paragraph

Trial report in European heart journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05225935 (Computed Tomography-Guided Catheter Ablation for Ventricular Tachycardia), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05225935 nacompletednot on this map

Computed Tomography-Guided Catheter Ablation for Ventricular Tachycardia (InEurHeart Study)

TypeinterventionalSponsorUniversity Hospital, BordeauxRan2022 to 2024Enrolled119ConditionsVentricular TachycardiaArmsimage-guided VT ablation strategy, conventional VT ablation strategy
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors.

Frederic SacherDepartment of Cardiac Pacing and Electrophysiology, Bordeaux University Hospital (CHU), Avenue du Haut Leveque, Bordeaux 33604, France.ORCID 0000-0001-8348-9320
Tobias ReichlinInselspital Bern, Bern, Switzerland.ORCID 0000-0002-7197-8415
Mathieu Le BloaCHU Vaudois, Lausanne, Switzerland.
Gregoire MassoulieCHU de Clermont-Ferrand, Clermont-Ferrand, France.
Xavier WaintraubPitié-Salpêtrière University Hospital, AP-HP, Paris, France.ORCID 0000-0001-5391-4007
Philippe MauryHopital Rangueil, CHU Toulouse, Toulouse, France.
Daniel ScherrMedical University of Graz, Austria, Graz, Austria.ORCID 0000-0001-5868-5493
Romain TixierDepartment of Cardiac Pacing and Electrophysiology, Bordeaux University Hospital (CHU), Avenue du Haut Leveque, Bordeaux 33604, France.ORCID 0000-0003-4093-0483
Benoit Guy-MoyatCHU Limoges, Limoges, France.
Josselin DuchateauDepartment of Cardiac Pacing and Electrophysiology, Bordeaux University Hospital (CHU), Avenue du Haut Leveque, Bordeaux 33604, France.ORCID 0000-0002-4367-1117
Christian MeyerDivision of Cardiology, EVK Düsseldorf, Dusseldorf, Germany.ORCID 0000-0003-0217-3960
Maxime SermesantINRIA, Sophia-Antipolis, France.ORCID 0000-0002-6256-8350
Allan PlantDepartment of Cardiac Pacing and Electrophysiology, Bordeaux University Hospital (CHU), Avenue du Haut Leveque, Bordeaux 33604, France.
Marine RoussetUnité de Sécurité et vigilance des essais cliniques-Direction de la recherche clinique et de l'innovation, Bordeaux University Hospital (CHU), Bordeaux, France.ORCID 0000-0002-3102-6866
Melanie A GunawardeneDepartment of Cardiology and Intensive Care Medicine, Asklepios Hospital St.Georg, Lohmuehlenstrasse 5, Hamburg, Germany.
Noemie BronnecDepartment of Cardiac Pacing and Electrophysiology, Bordeaux University Hospital (CHU), Avenue du Haut Leveque, Bordeaux 33604, France.
Estelle GandjbakhchPitié-Salpêtrière University Hospital, AP-HP, Paris, France.ORCID 0000-0002-4846-5021
Benjamin SacristanDepartment of Cardiac Pacing and Electrophysiology, Bordeaux University Hospital (CHU), Avenue du Haut Leveque, Bordeaux 33604, France.
Aurore GeorgetClinical Epidemiology Unit (USMR), Pôle de santé publique, CHU de Bordeaux, Bordeaux, France.
Geoffroy DitacDepartment of Cardiac Pacing and Electrophysiology, Bordeaux University Hospital (CHU), Avenue du Haut Leveque, Bordeaux 33604, France.ORCID 0000-0002-4833-4347
Sanna AzzouzErasmus School of Health Policy and Management, Erasmus University, Rotterdam, The Netherlands.
Michel HaissaguerreDepartment of Cardiac Pacing and Electrophysiology, Bordeaux University Hospital (CHU), Avenue du Haut Leveque, Bordeaux 33604, France.
Stephan WillemsDepartment of Cardiology and Intensive Care Medicine, Asklepios Hospital St.Georg, Lohmuehlenstrasse 5, Hamburg, Germany.ORCID 0000-0002-8890-5749
Nicolas DervalDepartment of Cardiac Pacing and Electrophysiology, Bordeaux University Hospital (CHU), Avenue du Haut Leveque, Bordeaux 33604, France.
Roland Richard TilzDepartment of Rhythmology, German Center for Cardiovascular Research (DZHK), Lubeck, Germany.
Mélèze HociniDepartment of Cardiac Pacing and Electrophysiology, Bordeaux University Hospital (CHU), Avenue du Haut Leveque, Bordeaux 33604, France.ORCID 0000-0002-7957-8766
Thomas DenekeRhönklinikum Campus, Bad Neustadt, Germany.ORCID 0000-0003-1379-1684
Thomas PambrunDepartment of Cardiac Pacing and Electrophysiology, Bordeaux University Hospital (CHU), Avenue du Haut Leveque, Bordeaux 33604, France.ORCID 0000-0001-6763-2350
Maureen Rutten-van MölkenErasmus School of Health Policy and Management, Erasmus University, Rotterdam, The Netherlands.
Helmut PürerfellnerOrdensklinikum Linz Elisabethinen, Linz, Austria.ORCID 0000-0002-8965-8495
Florian EnglertGerman Heart Center, München, Germany.ORCID 0000-0002-3014-4190
Elena SauerRhönklinikum Campus, Bad Neustadt, Germany.
Pierre JaisDepartment of Cardiac Pacing and Electrophysiology, Bordeaux University Hospital (CHU), Avenue du Haut Leveque, Bordeaux 33604, France.
Antoine BenardClinical Epidemiology Unit (USMR), Pôle de santé publique, CHU de Bordeaux, Bordeaux, France.
Hubert CochetIHU LIRYC, Electrophysiology and Heart Modelling Institute, University of Bordeaux, Bordeaux, France.

Funding

EIT Health 220639French GovernmentNational Research Agency ANR-10-IAHU-04National Research Agency ANR-24-DIME-0005
6 · The paper itself

Abstract

BACKGROUND AND

aimsCatheter ablation is performed in patients with recurrent ventricular tachycardia (VT) but remains complex and limited to experienced centres. Ventricular tachycardia ablation guided by pre-procedural imaging was shown promising in non-randomized trials. InEurHeart aims to evaluate computed tomography (CT)-guided VT ablation vs conventional ablation in a multicentre randomized controlled trial.

methodsIn 14 European centres, 113 patients with prior myocardial infarction and clinically significant VT were randomly assigned to CT-guided (n = 57) or conventional (n = 56) VT ablation. The primary objective was to demonstrate reduced procedural duration when using CT guidance. Secondary endpoints included efficacy (incidence and burden of ventricular arrhythmia), safety, as well as composite endpoints.

resultsThe primary endpoint showed a significant decrease in procedure time favouring CT-guided ablation: 149 ± 51 to 120 ± 50 min, -19% [95% confidence interval (CI) -32; -7]; P = .0027 in intention to treat, and 149 ± 51 to 107 ± 38 min, -28% (95% CI -40; -16); P < .0001 per protocol. Major adverse events occurred in two (3.5%) in the conventional group vs one (1.8%) in the CT-guided group [-1.8% (95% CI -7.9; 4.3)]. Ventricular tachycardia-free survival at 1 year was achieved in 37 (67.3%) patients for conventional vs 43 (76.8%) for CT-guided VT ablation [9.5% (95% CI -10.4; 29.4), P = NS]. Ventricular tachycardia burden was decreased by 90% in the CT-guided group.

conclusionsIn patients with ischaemic cardiomyopathy, CT-guided VT ablation reduces the procedure duration while maintaining a favourable efficacy and safety profile when compared with VT ablation without image integration.

Indexed as

Catheter AblationTachycardia, VentricularTomography, X-Ray ComputedAgedFemaleHumansMaleMiddle AgedSurgery, Computer-AssistedTreatment OutcomeCardiac CT scanCardiac imagingProcedure outcomeVentricular tachycardia ablation

Identifiers

PMID41667137
PMCPMC13291909

What Socratic holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.