Evidence map›Paper›PMID 41667508›Full record

ArticleNPJ science of food2026

Effects of Antarctic krill oil on lipid profiles and SPM levels in rats over time.

Weibo Lu, Ning Huangfu, Lijun Ge, Huixiang Wu, Shitong Wang, Jiahui Wu, Jing Xue, Chunlai Zeng, Tianming Xuan, Liqun Cui and 11 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NPJ science of food, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Weibo Lu *Laboratory of Food Nutrition and Clinical Research, Institute of Seafood, Zhejiang Gongshang University, Hangzhou, China.
Ning Huangfu *Key Laboratory of Precision Medicine for Atherosclerotic Diseases of Zhejiang Province, Department of Cardiology, The First Affiliated Hospital of Ningbo University, Ningbo, China.
Lijun GeLaboratory of Food Nutrition and Clinical Research, Institute of Seafood, Zhejiang Gongshang University, Hangzhou, China.
Huixiang WuLaboratory of Food Nutrition and Clinical Research, Institute of Seafood, Zhejiang Gongshang University, Hangzhou, China.
Shitong WangLaboratory of Food Nutrition and Clinical Research, Institute of Seafood, Zhejiang Gongshang University, Hangzhou, China.
Jiahui WuLaboratory of Food Nutrition and Clinical Research, Institute of Seafood, Zhejiang Gongshang University, Hangzhou, China.
Jing XueLaboratory of Food Nutrition and Clinical Research, Institute of Seafood, Zhejiang Gongshang University, Hangzhou, China.
Chunlai ZengDepartment of Cardiology, Central Laboratory of Lishui Hospital of Wenzhou Medical University, The First Affiliated Hospital of Lishui University, Lishui People's Hospital, Lishui, Zhejiang, China.
Tianming XuanDepartment of Cardiovascular Medicine, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Liqun CuiHangzhou Linping Hospital of Traditional Chinese Medicine, Hangzhou, China.
Jianliang ZhangHangzhou Linping Hospital of Traditional Chinese Medicine, Hangzhou, China.
Linhua WangHangzhou Linping Hospital of Traditional Chinese Medicine, Hangzhou, China.
Qingcheng WangHangzhou Linping Hospital of Traditional Chinese Medicine, Hangzhou, China.
Jie YuanHangzhou Linping Hospital of Traditional Chinese Medicine, Hangzhou, China.
Hongqiang WangHangzhou Linping Hospital of Traditional Chinese Medicine, Hangzhou, China.
Hong YuanDepartment of Cardiovascular Medicine, First People's Hospital of Linping District, Hangzhou, China.
Xinghua BaiDepartment of Cardiovascular Medicine, First People's Hospital of Linping District, Hangzhou, China.
Huamin YuDepartment of Cardiovascular Medicine, First People's Hospital of Linping District, Hangzhou, China.
Xi ChenKey Laboratory of Precision Medicine for Atherosclerotic Diseases of Zhejiang Province, Department of Cardiology, The First Affiliated Hospital of Ningbo University, Ningbo, China.
Qing ShenLaboratory of Food Nutrition and Clinical Research, Institute of Seafood, Zhejiang Gongshang University, Hangzhou, China. leonqshen@163.com.
Keyun ChengPanvascular Diseases Research Center, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People's Hospital, Quzhou, China. ky_cheng@126.com.

Funding

Hangzhou Medical Health Technology Project B20200116Hangzhou Medical Health Technology Project B20231798Key Laboratory of Precision Medicine for Atherosclerotic Diseases of Zhejiang Province SZKF2023YB012Linping District Agricultural and Social Development Research Projects 2022015Linping Medical Health Technology Project LPWJ2022-01-03Linping Medical Health Technology Project LPWJ2023-01-16Linping Medical Health Technology Project LPWJ2023-02-38National Natural Science Foundation of China 82200489Ningbo Youth Science and Technology Innovation Leading Talent Project 2024QL027Zhejiang Medical Association Clinical Medical Research Special Project 2023ZYC-Z34Zhejiang Medical Health Science and Technology Plan 2022KY1062Zhejiang Medical Health Science and Technology Plan 2023KY091Zhejiang Medical Health Science and Technology Plan 2023XY006Zhejiang Pharmaceutical Society Hospital Pharmacy Special Research Funding Project 2023ZYY34Zhejiang Provincial Public Welfare Technology Research Project LTGY24H020004
6 · The paper itself

Abstract

Antarctic krill oil (KO) is a richsource of omega-3 polyunsaturated fatty acids (PUFAs). Endogenous PUFA-derived specialized pro-resolving mediators (SPMs) have garnered attention due to their beneficial effects on body, especially the cardiovascular system. This study integrated non-targeted and targeted lipidomics to investigate KO's time-dependent effects on the comprehensive lipid profile and SPMs in rats. After 1- and 6-week supplementation, KO significantly altered lipid profiles, reducing arachidonic acid (ARA, 20:4)-containing lipids while elevating eicosapentaenoic acid (EPA, 20:5)/docosahexaenoic acid (DHA, 22:6)-containing lipids. Targeted analysis identified and quantified 33 PUFA-derived oxylipins, including derivatives of ARA, 8 derivatives of EPA, and 13 derivatives of DHA. Notably, KO consumption substantially decreased pro-inflammatory oxylipins like LTB

Identifiers

PMID41667508
PMCPMC13000294

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.