ArticlePlant cell reports2026
CtSnRK2.6 from Cynanchum thesioides confers drought stress resistance in plants.
Article in Plant cell reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
key messageWe identified ABA- and drought-induced CtSnRK2.6 from Cynanchum thesioides; its protein localizes to the nucleus and plasma membrane. It boosts drought resistance of C. thesioides and Arabidopsis by regulating antioxidant and stress-responsive genes, while its silencing impairs C. thesioides' drought tolerance. CtSnRK2.6 interacts with CtPP2C1/3, and CtPP2C1 binds CtPYL1/5/6. This study clarifies its core role and interaction network in the ABA pathway, laying a theoretical foundation for elucidating C. thesioides' stress resistance mechanisms. Sucrose non-fermenting-1-related protein kinase 2 (SnRK2) is a core regulator in the plant abiotic stress response pathway. In this study, we identified a Cynanchum thesioides gene CtSnRK2.6 that is homologous to Arabidopsis AtSnRK2.6, and this gene is significantly induced by drought stress and abscisic acid (ABA) treatment. Subcellular localization analysis revealed that the CtSnRK2.6 protein is localized in the nucleus and plasma membrane. Functional verification results demonstrated that overexpression of CtSnRK2.6 significantly enhances osmotic stress tolerance in yeast and drought resistance in Arabidopsis; under drought conditions, the overexpressing plants not only maintain a superior phenotype, but also exhibit significantly increased fresh weight and chlorophyll content, markedly enhanced antioxidant enzyme activity, significantly reduced accumulation of reactive oxygen species (O₂⁻, H₂O₂) and malondialdehyde (MDA), as well as significantly upregulated expression levels of stress-responsive genes. Conversely, inhibition of CtSnRK2.6 expression via Tobacco Rattle Virus (TRV)-mediated gene silencing technology significantly impairs the drought resistance of C. thesioides. Yeast two-hybrid (Y2H) and bimolecular fluorescence complementation (BiFC) assays further confirmed that CtSnRK2.6 can directly interact with CtPP2C1 and CtPP2C3; CtPP2C1 can interact with CtPYL1, CtPYL5, and CtPYL6, respectively. Taken together, this study clarifies the key role of CtSnRK2.6 in enhancing drought resistance by regulating the plant antioxidant system, and reveals its interaction network with PYL and PP2C proteins, which are core components of the ABA signaling pathway. These findings provide important theoretical support for in-depth elucidation of the stress adaptation mechanism of C. thesioides.
Indexed as
Identifiers
41667739What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.