Evidence map›Paper›PMID 41668761›Full record

ArticleGeoHealth2026

Associations Between Polybrominated Diphenyl Ethers and Biological Aging in NHANES 2005-2010 and 2015-2016.

Yan Chen, Ruilan Gong, Qianzhu Li, Xinrui Ma

Abstract read
In one paragraph

Article in GeoHealth, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yan ChenDepartment of Physiology Harbin Medical University Harbin China.
Ruilan GongDepartment of Physiology Harbin Medical University Harbin China.
Qianzhu LiDepartment of Nutrition and Food Hygiene The National Key Discipline School of Public Health Harbin Medical University Harbin P. R. China.
Xinrui MaThe Academic Department of Science and Technology Harbin Medical University Cancer Hospital Harbin China.ORCID https://orcid.org/0009-0004-7932-2834

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The associations of polybrominated diphenyl ethers (PBDEs) with biological aging are unclear. This study explores the possible relationship between PBDEs and accelerated aging. Cross-sectional data from 6,091 subjects of the National Health and Nutrition Examination Survey (NHANES) 2005-2010 and 2015-2016 are analyzed. Serum PBDE concentrations are quantified via automated liquid-liquid extraction and subsequent sample purification, with seven PBDEs displaying a capture rate higher than 70%, identified as the exposure. Homeostatic dysregulation (HD), Klemera-Doubal method (KDM), phenoAge (PA), and allostatic load (AL) are utilized to assess biological aging. The associations are assessed with weighted multivariate linear regression models, restricted cubic spline (RCS), weighted quantile sum regression, and Quantile G-computation analysis. Regarding individual exposures, significant positive associations of PBDE47, PBDE99, PBDE100, PBDE154, and PBDE85 with HD, KDM residual, and PA residual, and PBDE100 with AL (

Indexed as

biological agingNHANESPBDEsQGC analysisWQS regression

Identifiers

PMID41668761
PMCPMC12883683

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.