ArticleAdvanced biomedical research2025
Homocysteine and Peripheral White Blood Cell Count-derived Ratios: Insights from Healthy Population.
Article in Advanced biomedical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Homocysteine (Hcy) and dyslipidemia are established risk parameters of atherosclerosis. Considerable research has been conducted using ratios of lymphocytes to other cellular components of the peripheral white blood cell count (PBC) as biomarkers. The association between white blood cell (WBC) count and body mass index, total cholesterol, triglycerides, glucose, blood pressure, and lifestyle factors has been studied. The present study explored the connections of PBC-derived ratios with Hcy and lipid parameters in healthy individuals. Materials and Methods: Hcy levels were assessed in residual samples collected from individuals visiting the hospital for their annual check-up. Lipid and leukocyte profile was retrieved from the Laboratory Information System (LIS). Neutrophil-to-lymphocyte ratio (NLR), lymphocyte-to-monocyte ratio (LMR), monocyte-high-density lipoprotein ratio (MHR), and lymphocyte-to-high-density lipoprotein (HDL) cholesterol ratio (LHR) were calculated. Bivariate correlation was used to assess the association between Hcy, lipid profile, and PBC-derived ratios. Results: Hyperhomocystinemia (HHcy) was detected in 43.54% of healthy individuals and was associated with a significant increase in eosinophils ( Conclusion: The study reveals that HHcy is associated with significant alterations in PBCs.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.