ArticleFrontiers in medicine2026
Optimization of modified CT severity index by incorporating lymphocyte-to-monocyte ratio for early stratification in acute pancreatitis: a single-center validation study.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Acute pancreatitis is a common digestive system emergency with heterogeneous clinical courses, and early accurate stratification is crucial for guiding treatment, improving prognosis, and reducing mortality. Existing scoring systems such as the Modified CT Severity Index (MCTSI) primarily rely on imaging features, but alone may not fully reflect inflammatory status, while inflammatory markers like the Lymphocyte-to-Monocyte Ratio (LMR) show potential in predicting disease severity; however, studies combining both are insufficient. Objective: To investigate the value of integrating LMR with MCTSI to construct a new scoring system (MCTSI-LMR) for early stratification in acute pancreatitis, optimizing clinical predictive efficacy. Methods: A total of 216 patients with acute pancreatitis admitted to Hefei Third People's Hospital from April 2022 to January 2025 were selected as the study subjects. All patients were divided into mild group (65 cases), moderately severe group (108 cases), and severe group (43 cases) according to the Atlanta classification criteria (2012 revision). All patients underwent abdominal CT scanning and complete blood count within 24 hours of admission to calculate MCTSI scores and LMR values. Using clinical outcomes as the gold standard, inter-group indicator differences and the diagnostic efficacy of the combined score were compared. Results: Based on disease severity, the severe group had significantly lower LMR values than the mild and moderately severe groups ( Conclusion: The application of the MCTSI-LMR score in early stratification of acute pancreatitis can significantly enhance predictive efficacy, with notable differences combining imaging and inflammatory markers, providing a reliable tool for clinical early intervention and worthy of promotion and application.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.