ArticleFrontiers in medicine2025
Analysis of factors influencing hemoglobin target achievement in maintenance hemodialysis patients in Wuhan, China.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: This study identified key factors influencing hemoglobin (Hb) target achievement (≥110 g/L) in maintenance hemodialysis (MHD) patients in Wuhan to guide improvement strategies. Methods: A multicenter retrospective study (January 2019-December 2023) included 4,906 MHD patients from 70 dialysis centers in Wuhan. Data on demographics, dialysis-related parameters, pre-dialysis laboratory indices, and medication use were collected. Patients were categorized into target (Hb ≥ 110 g/L) and non-target group (Hb < 110 g/L). Group differences were analyzed, and binary multivariate logistic regression identified independent factors. Results: A total of 4,906 MHD patients from 70 dialysis centers were included in this study. Multivariate logistic regression analysis identified female sex ( Conclusion: Hb target achievement in Wuhan MHD patients is influenced by a complex interplay of demographic (sex), clinical (vascular access type, dialysis adequacy and frequency, blood pressure management, inflammatory status, mineral/nutrition/iron status), therapeutic (LMWH and LC management), and socioeconomic factors (insurance). Targeting modifiable factors is crucial for optimizing anemia management.
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