ArticleQuantitative imaging in medicine and surgery2026
Association of splenic contraction with stroke severity and diabetes mellitus in patients with acute ischemic stroke.
Article in Quantitative imaging in medicine and surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Antler stem cells effectively alleviate the symptoms of cerebral ischemic injury via immunomodulation of the spleen.Cell death discovery · 2026Article
- Erratum: Association of splenic contraction with stroke severity and diabetes mellitus in patients with acute ischemic stroke.Quantitative imaging in medicine and surgery · 2026Article
Corrections and comments
- Erratum issued
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Splenic contraction (SC) is characterized by reduced splenic volume (SV) due to the release of splenocytes into systemic circulation. This study aimed to investigate the differences between patients with acute ischemic stroke with and without SC and identify SC-associated factors. Methods: In this retrospective study, 79 patients with acute ischemic stroke who underwent abdominal computed tomography within 5 years before and within 7 days after stroke onset were analyzed. Patients were categorized into SC (SV change ≤-5 cm Results: The SC group had significantly higher National Institutes of Health Stroke Scale (NIHSS) scores on admission compared to the non-SC group {median 7 [interquartile range (IQR) 3-12] Conclusions: Patients with SC demonstrated significantly higher admission NIHSS scores, suggesting that SC is associated with greater neurological deficits during the acute phase of ischemic stroke. DM was associated with a lower incidence of post-stroke SC, possibly due to DM-associated pathophysiology such as blunted sympathetic response or oxidative stress-induced splenic dysfunction. These findings emphasize the potential role of the spleen in stroke pathophysiology and highlight its potential as a therapeutic target.
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