ArticleCureus2026
A Case Report and Literature Review of Steroid-Resistant Granulomatous Mastitis: Dramatic Response to Methotrexate Following Failed Drainage and Corticosteroid Therapy.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Idiopathic granulomatous mastitis is an uncommon benign inflammatory breast condition that often follows a prolonged and relapsing course and may closely resemble infection or malignancy, leading to repeated interventions. We describe a young multiparous woman with a long history of recurrent breast abscesses and persistent draining sinuses who failed multiple surgical drainages and prolonged systemic corticosteroid therapy. Ongoing disease activity prompted a shift in management to immunomodulatory treatment, after which the patient experienced gradual but complete clinical and radiologic resolution with sustained remission on follow-up. This case illustrates the potential role of methotrexate as an effective alternative in refractory disease and highlights the importance of considering steroid-sparing strategies to reduce morbidity and avoid unnecessary repeated surgical procedures.
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