Evidence mapPaperPMID 41669930Full record

ReviewThe Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology2026

Preexisting Liver Disease and Pregnancy: Optimizing Care to Optimize Outcomes.

Ilkay Ergenc, Alexandra Frolkis, Michael Heneghan

Abstract readReview
In one paragraph

Review in The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Pregnancy in Primary Biliary Cholangitis: A Single-Center Experience Emphasizing the Need for Postpartum Monitoring.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ilkay ErgencThe Roger Williams Institute of Liver Studies, King's College Hospital, London, UK.
Alexandra FrolkisDivision of Gastroenterology and Hepatology, Department of Medicine, University of Calgary, Calgary, Canada.
Michael HeneghanThe Roger Williams Institute of Liver Studies, King's College Hospital, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Preexisting liver disease, particularly the presence of cirrhosis and portal hypertension (PHT), presents a significant challenge during gestation,  necessitating close collaboration between obstetric and hepatology/gastroenterology teams. Women with underlying liver conditions face an increased likelihood of adverse maternal and fetal outcomes. Proactive identification and management of the potential risks associated with pregnancy in this patient group is therefore crucial. While the desire to start a family is deeply personal, each pregnancy carries unique risks requiring careful consideration. Although no single recommendation can comprehensively address all forms of liver disease, pregnancy in women with underlying hepatic conditions can be both safe and achievable when managed througha multidisciplinary team approach, involving the mother and her partner from the preconception stage through to the postpartum period. This review summarizes the current evidence regarding the risks and management strategies for pregnancy complicated by preexisting liver disease, including cirrhosis and PHT, steatotic liver disease, viral hepatitis, autoimmune liver disease, and liver transplant recipients.   Cite this article as: I E, A F, MA H. Preexisting liver disease and pregnancy: optimizing care to optimize outcomes. Turk J Gastroenterol. 2026;37(2):146-160.

Indexed as

Liver DiseasesPregnancy ComplicationsFemaleHumansHypertension, PortalLiver CirrhosisLiver TransplantationPregnancyPregnancy Outcome

Identifiers

PMID41669930
PMCPMC12910311

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.