Evidence map›Paper›PMID 41670838›Full record

ArticleOdontology2026

Clinical decision accuracy in endodontic treatment of patients with systemic diseases: a comparative analysis using different artificial intelligence models.

Ayşegül Eroğlu, İpek Eraslan Akyüz, Emre Yılmaz, Salih Düzgün

Abstract read
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In one paragraph

Article in Odontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ayşegül EroğluDepartment of Endodontics, Faculty of Dentistry, Erciyes University, 38039, Melikgazi, Kayseri, Türkiye.ORCID http://orcid.org/0009-0008-5588-0830
İpek Eraslan AkyüzDepartment of Endodontics, Faculty of Dentistry, Erciyes University, 38039, Melikgazi, Kayseri, Türkiye.ORCID http://orcid.org/0009-0004-0963-9617
Emre YılmazDepartment of Family Medicine, Faculty of Medicine, Erciyes University, Kayseri, Türkiye.ORCID http://orcid.org/0009-0009-8353-8159
Salih DüzgünDepartment of Endodontics, Faculty of Dentistry, Erciyes University, 38039, Melikgazi, Kayseri, Türkiye. dtsalihduzgun@gmail.com.ORCID http://orcid.org/0000-0002-0868-3390

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aims to compare the clinical decision-making accuracy of different artificial intelligence (AI) models in endodontic treatment planning for patients with systemic diseases. A scenario-based, cross-sectional educational study was conducted using 40 standardized clinical scenarios representing ten commonly encountered systemic conditions affecting endodontic care. Scenarios were developed based on international endodontic and medical guidelines and reviewed by medical specialists and experienced endodontists. Four AI models, ChatGPT-5.1, Gemini 2.5 Pro, Gemini 2.5 Flash, and ChatGPT-3.5, were queried using identical, standardized prompts within fully isolated interaction environments to prevent contextual memory effects. AI-generated responses were independently evaluated by two calibrated endodontists using a predefined 10-point scoring system across four clinical domains. Clinical accuracy was categorized as high, partial, or incorrect. Nonparametric statistical analyses were performed. No statistically significant differences were observed among AI models in overall clinical decision accuracy or domain-specific scores (Friedman test, p > 0.05). Although categorical analysis revealed an overall difference in the proportion of high-accuracy responses (Cochran's Q, p = 0.007), post hoc comparisons did not demonstrate significant pairwise differences. Deviation analysis revealed comparable proximity of all models to the expert-defined optimal decisions, with greater variability observed for the Gemini 2.5 Flash. Current AI models demonstrate comparable clinical decision-making performance in endodontic scenarios involving medically compromised patients. While descriptive trends were observed, no single model consistently outperformed others. AI systems may serve as supportive decision-making tools when used under professional supervision, but should not replace clinical judgment.

Indexed as

Artificial intelligenceEndodonticsLarge language modelsSystemic diseases

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.