Evidence map›Paper›PMID 41671109›Full record

SynthesisJournal of evidence-based integrative medicine

Impact of Syndrome Differentiation on Treatment Effects and side Effects of Chinese Herbal Medicine in Randomized Controlled Trials: A Meta-Epidemiological Study.

Claire C W Zhong, Betty Huan Wang, Mary Y Jiang, Irene X Y Wu, Leonard Ho, Fai Fai Ho, Shan Shan Xu, Ming Hong Kwong, Joson H S Zhou, Jason K C Lam and 1 more

Abstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of evidence-based integrative medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Claire C W ZhongJockey Club School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong.ORCID 0000-0001-8079-3634
Betty Huan WangJockey Club School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong.ORCID 0000-0001-7337-9005
Mary Y JiangSchool of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong.
Irene X Y WuXiangya School of Public Health, Central South University, Changsha, China.
Leonard HoJockey Club School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong.
Fai Fai HoSchool of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong.
Shan Shan XuJockey Club School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong.
Ming Hong KwongJockey Club School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong.
Joson H S ZhouJockey Club School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong.
Jason K C LamJockey Club School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong.
Vincent C H ChungJockey Club School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ObjectiveIn Traditional Chinese medicine (TCM), syndrome differentiation is considered to be an essential diagnostic process for tailoring Chinese herbal medicine (CHM) treatments to individual patients. We conducted a meta-epidemiological study to evaluate the potential impact of syndrome differentiation on improving effect estimates in randomized controlled trials (RCTs).Study Design and SettingSeven databases were searched to identify systematic reviews (SRs) published between 2021 and 2022 that pooled RCTs evaluating CHM treatment effects or side effects. Meta-epidemiological analyses were conducted using a two-step approach. Subgroup analyses were performed based on the disease category, outcome nature, and funding.ResultsWe included 137 SRs comprising 2,064 RCTs. The results demonstrated small and statistically nonsignificant differences in both treatment effects (ROR: 0.93, 95% confidence interval (CI): 0.86 to 1.00,

Indexed as

Drugs, Chinese HerbalMedicine, Chinese TraditionalDiagnosis, DifferentialHumansRandomized Controlled Trials as TopicTreatment OutcomeDrugs, Chinese HerbalChinese herbaldiagnosisdifferentialdrugsepidemiologic studiesmeta-Analysis as topicrandomized controlled trialtreatment outcome

Identifiers

PMID41671109
PMCPMC12894648

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.