Evidence map›Paper›PMID 41673269›Full record

ArticleAnalytical sciences : the international journal of the Japan Society for Analytical Chemistry2026

Developing an isoflavone-based fluorescent probe for monitoring carboxylesterase on studying medicine-food homology samples.

Juan Meng, Yangyang Guo, Fang Wang, Yingmiao Lai, Yingying Deng, Hongcun Liu

Abstract read
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In one paragraph

Article in Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Juan Meng *College of Preparatory Education, Guangxi Minzu University, Nanning, 530008, China.
Yangyang Guo *Chongzuo Key Laboratory of Comprehensive Utilization Technology of Manganese Resources, Guangxi Key Laboratory for High-value Utilization of Manganese Resources, College of Chemistry and Biological Engineering, Guangxi Minzu Normal University, Chongzuo, 532200, China.
Fang WangGuangxi Key Laboratory for Polysaccharide Materials and Modifications, School of Marine Sciences and Biotechnology, Guangxi Minzu University, Nanning, 530008, China.
Yingmiao LaiCollege of Preparatory Education, Guangxi Minzu University, Nanning, 530008, China.
Yingying DengCollege of Preparatory Education, Guangxi Minzu University, Nanning, 530008, China.
Hongcun LiuGuangxi Key Laboratory for Polysaccharide Materials and Modifications, School of Marine Sciences and Biotechnology, Guangxi Minzu University, Nanning, 530008, China. gxunliuhongcun@163.com.

Funding

Project for Enhancing Young and Middle-aged Teacher's Research Basis Ability in Colleges of Guangxi 2025KY0210Project for Guangxi Minzu Normal University 2024YB076Project for Minority Preparatory Education Base of Guangxi YJJDB202401
6 · The paper itself

Abstract

Herein, for monitoring the carboxylesterase (CE) level on studying medicine-food homology samples, an isoflavone-based fluorescent probe, IFone-CE, was developed on the basis of the representative Formonetin and the extended saturated fatty acidic chain as the recognition group. A typical turning-on was established, which remained the modification potential. The probe IFone-CE suggested general advantages including a relatively rapid response, stable optical performance in various working conditions of pH, temperature, and storage. It also exhibited practical linear range, high sensitivity, high selectivity, and low cyto-toxicity. The solution system containing IFone-CE achieved monitoring the biological efficacy of medicine-food homology samples. In the confocal imaging, IFone-CE realized the reduction and promotion effect of the samples in living colorectal cells. This work raised beneficial insights for the effective utilization of resources and medicinal chemistry research.

Indexed as

CarboxylesteraseFluorescent DyesIsoflavonesFood AnalysisCarboxylesteraseFluorescent DyesIsoflavonesCarboxylesteraseFluorescent probeIntracellular imagingIsoflavone analoguesMedicine-food homology

Identifiers

PMID41673269

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.