Evidence map›Paper›PMID 41673403›Full record

ArticleNature communications2026

Transposable elements hitchhike on Starships across fungal genomes.

Hanne Griem-Krey, Júlia de Fraga Sant'Ana, Ursula Oggenfuss, Yohana Porto Calegari-Alves, Ana Luiza Marques, Markus Berger, Lucélia Santi, Walter O Beys-da-Silva, Michael Habig

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hanne Griem-KreyFungal Evolutionary Genetics, Christian-Albrechts University of Kiel, Kiel, Germany.ORCID 0009-0009-3504-404X
Júlia de Fraga Sant'AnaFaculdade de Farmácia; Centro de Biotecnologia, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre/RS, Brazil.ORCID 0009-0006-1405-7536
Ursula OggenfussLaboratory of Evolutionary Genetics, Institute of Biology, University of Neuchâtel, Neuchâtel, Switzerland.
Yohana Porto Calegari-AlvesFaculdade de Farmácia; Centro de Biotecnologia, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre/RS, Brazil.
Ana Luiza MarquesFaculdade de Farmácia; Centro de Biotecnologia, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre/RS, Brazil.
Markus BergerHospital de Clínicas de Porto Alegre, Porto Alegre/RS, Brazil.
Lucélia SantiFaculdade de Farmácia; Centro de Biotecnologia, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre/RS, Brazil.ORCID 0000-0002-5698-7006
Walter O Beys-da-SilvaFaculdade de Farmácia; Centro de Biotecnologia, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre/RS, Brazil. walter.beys@ufrgs.br.ORCID 0000-0001-8329-7839
Michael HabigFungal Evolutionary Genetics, Christian-Albrechts University of Kiel, Kiel, Germany. mhabig@bot.uni-kiel.de.ORCID 0000-0002-8059-806X

Funding

EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 European Research Council (H2020 Excellent Science - European Research Council) Project 101219076 (MobiChrom)
6 · The paper itself

Abstract

Horizontal transfer of transposable elements (TEs) is widespread in eukaryotes, driving genetic variation and often associated with bursts of TE activity. Here, we report a recent TE burst in the insect-pathogenic fungus Metarhizium anisopliae. The actively transposing TEs were likely introduced via hitchhiking on a so-called Starship, a class of large, horizontally transferable transposons. This TE burst likely triggered extensive structural reshuffling across all chromosomes, which was associated with loss of pathogenicity. Expanding our analysis to other fungi, we found that Starship-mediated horizontal transfer of TEs is a general phenomenon. Most (75%) of 522 reported Starships harbor TEs; many of which show evidence of a recent burst, in some cases likely starting from the TE copies on the Starship itself. A high fraction of TEs located on Starships also shows signatures of past horizontal transfer. Collectively, our results establish Starships as major vectors of horizontal TE transfer.

Indexed as

DNA Transposable ElementsGene Transfer, HorizontalGenome, FungalMetarhiziumEvolution, MolecularDNA Transposable Elements

Identifiers

PMID41673403
PMCPMC13004909

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.