Evidence map›Paper›PMID 41673779›Full record

ReviewBiomarker research2026

Migrasomes: a journey from biogenesis to multifaceted roles in health and disease.

Yuqing Zhao, Shijing Tang, Jingying Zhou, Yang Luo, Liang Duan

Abstract readReview
In one paragraph

Review in Biomarker research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yuqing ZhaoDepartment of Laboratory Medicine, The Second Affiliated Hospital of Chongqing Medical University, No. 74 linjiang Road, Yu Zhong District, Chongqing, 400010, China.
Shijing TangDepartment of Laboratory Medicine, The Second Affiliated Hospital of Chongqing Medical University, No. 74 linjiang Road, Yu Zhong District, Chongqing, 400010, China.
Jingying ZhouSchool of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, Hong Kong SAR, 999077, China.
Yang LuoDepartment of Laboratory Medicine, Chongqing Center for Clinical Laboratory, Chongqing General Hospital, School of Medicine, Chongqing Academy of Medical Sciences, Chongqing University, No. 118 Xingguang Avenue, Yubei District, Chongqing, 401147, China. luoy@cqu.edu.cn.
Liang DuanDepartment of Laboratory Medicine, The Second Affiliated Hospital of Chongqing Medical University, No. 74 linjiang Road, Yu Zhong District, Chongqing, 400010, China. duanliang@cqmu.edu.cn.

Funding

Chongqing medical scientific research project (Joint project of Chongqing Health Commission and Science and Technology Bureau) 2025ZDXM016National Natural Science Foundation of China 82472354Natural Science Foundation of Chongqing Municipality CSTB2023NSCQMSX0037Senior Medical Talents Program of Chongqing for Young and Middle-aged 2022-15
6 · The paper itself

Abstract

Migrasomes are newly identified extracellular organelles that form on the retraction fibers of migrating cells. Characterized by their pomegranate-like, membrane-bound structure, they encapsulate diverse molecular cargo, including proteins, lipids, RNA, and even damaged mitochondria. The biogenesis of migrasomes is a highly regulated, multi-stage process that depends on cell migration and requires an interplay between specific molecules and membrane mechanical stresses. Functionally, migrasomes play pivotal roles in intercellular communication by mediating the spatial transfer of signals and components. This review provides an overview of migrasome biology, covering their biogenesis mechanisms, distinctions from other types of vesicles, and their dual roles in physiology and pathology. Furthermore, we discuss the potential of migrasomes in disease diagnosis and therapeutic applications.

Indexed as

BiomarkerDiseaseExtracellular vesiclesMigrasomes

Identifiers

PMID41673779
PMCPMC12922388

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.