ArticleiMetaOmics2025
Haplotype-resolved genome and pan-genome graphs reveal the impacts of structural variation on functional genome and feather colors in chickens.
Article in iMetaOmics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- Multi-omics integration and artificial intelligence for the conservation and utilization of local chicken genetic resources.Poultry science · 2026Review
- Two telomere-to-telomere Nelumbo genome assemblies reveal domestication history and empower precision breeding.Nature communications · 2026Article
- Three Near telomere-to-telomere Genomes for Gardenia jasminoides.Scientific data · 2026Article
- Pan-3D Genome Analysis Reveals the Roles of Structural Variation in Chicken Chromatin Architectures, Domestication and Production Traits.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Unlocking growth potential in Wenchang chickens: A 21 K genotyping array for trait-associated structural variations.Poultry science · 2025Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Structural variation (SV) refers to a wide range of genetic variations that significantly affect genome biology and complex phenotypes. However, the population-level SV landscape and its functional impacts on chickens are largely unknown. Here, we generated haplotype-resolved genome assemblies for the Chinese Wenchang chicken and then integrated them with another 29 assemblies and 354 genome resequencing data to construct a pan-genome graph for SV genotyping. We detected 185,205 high-confidence SVs and found that one-third of them were derived from homology-based and transposable element (TE) insertion-based mutational mechanisms. By examining the ChickenGTEx resource, we discovered 1728 SVs associated with molecular phenotypes (e.g., gene expression and alternative splicing), including a 2.7-kb insertion in the exon of the
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.