Evidence map›Paper›PMID 41674567›Full record

ArticleiMetaOmics2025

Leveraging genetic data for female breast cancer prevention and therapy: Perspectives from Mendelian randomization.

Danqi Huang, Jingbo Zhai, Min Yang, Wei Xiong, Huilin Wang, Yang Bai, Jinqiu Yuan, Quan Wang, Bobo Zheng, Jingyi Liu and 6 more

Abstract readLetter
In one paragraph

Article in iMetaOmics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Danqi HuangOffice of Cancer Screening, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China.
Jingbo ZhaiSchool of Public Health Tianjin University of Traditional Chinese Medicine Tianjin China.
Min YangDepartment of Comprehensive Intervention, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China.
Wei XiongDepartment of Gynecology Endocrine & Reproductive Center, National Clinical Research Center for Obstetric & Gynecologic Diseases Department of Obstetrics and Gynecology, Peking Union Medical College Hospital Peking Union Medical College/Chinese Academy of Medical Sciences Beijing China.
Huilin WangOffice of Cancer Screening, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China.
Yang BaiThe Second Hospital & Clinical Medical School Lanzhou University Lanzhou China.
Jinqiu YuanDepartment of Epidemiology and Biostatistics, Clinical Big Data Research Center, The Seventh Affiliated Hospital Sun Yat-sen University Shenzhen China.
Quan WangAmbulatory Surgery Center of Xijing Hospital Fourth Military Medical University Xi'an China.
Bobo ZhengDepartment of General Surgery Shaanxi Provincial People's Hospital Xi'an China.
Jingyi LiuOffice of Cancer Screening, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China.
Shengling QinDepartment of Comprehensive Intervention, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China.
Rui SunDepartment of Comprehensive Intervention, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China.
Jinhui TianEvidence-Based Medicine Center, School of Basic Medicine Science Lanzhou University Lanzhou China.
Wenbo MengDepartment of General Surgery The First Hospital of Lanzhou University Lanzhou China.
Jianping HuangCollaborative Innovation Center for Western Ecological Safety, College of Atmospheric Sciences Lanzhou University Lanzhou China.
Jiang LiOffice of Cancer Screening, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China.ORCID https://orcid.org/0000-0001-8244-0349

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leveraging genome-wide association studies, Mendelian randomization analysis has been applied to explore the potential causal associations between various risk factors and female breast cancer, predict the efficacy and adverse effects of pre-existing and new-onset drugs, and evaluate opportunities of drug repurposing for the therapy of female breast cancer.

Identifiers

PMID41674567
PMCPMC12806021

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.