ArticleiMetaOmics2025
Dual-pronged genome engineering: Enhancing crop resistance through elite allele pyramiding and susceptibility gene editing.
Article in iMetaOmics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
2 authors.
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Abstract
Developing durable crop disease resistance remains a primary breeding objective, achievable through pyramiding resistance genes and editing susceptibility (S) genes. A recent study identified 10 stable Verticillium wilt resistance genes and eight negative regulators via integrated genome-wide association studies and transcriptome-wide association studies-eQTL analyses in upland cotton. Both pyramiding resistance alleles and CRISPR-mediated knockout of S-genes significantly reduced disease severity. These findings enable rapid implementation of disease resistance improvement in the genomics era.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.