SynthesisFrontiers in cellular and infection microbiology2026
Risk factors for invasive
Synthesis in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Article
- Multiloculated Klebsiella liver abscess successfully treated with early laparoscopic drainage after failed percutaneous drainage: a case report.AME case reports · 2026Article
- The Abscess That Was Cancer: Pyogenic Liver Abscess as the Initial Manifestation of Hepatocellular Carcinoma in a Noncirrhotic Patient.Case reports in hepatology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: Invasive Methods: Eight databases were retrieved. The Newcastle-Ottawa Scale and AHRQ criteria were utilized to assess the studies for quality. Stata software was used for pooling the effect size odds ratio (OR) and for subgroup analysis, sensitivity analysis, and regression analysis. Publication bias was examined leveraging funnel plots and Egger's test. Results: A total of 18 studies (cross-sectional, cohort, case-control studies) were included, with 3,133 patients. The meta-analysis revealed that the following factors were linked to a significantly elevated risk of IKPLAS: history of smoking or alcohol consumption (OR = 1.61, 95% CI: 1.05, 2.45, p = 0.028), diabetes (OR = 1.93, 95% CI: 1.49, 2.51, p<0.001), liver disease (OR = 1.66, 95% CI: 1.01, 2.73, p = 0.044), elevated sequential organ failure assessment (SOFA) score (OR = 1.71, 95% CI: 1.27, 2.30, p<0.001), septic shock (OR = 3.30, 95% CI: 1.70, 6.37,p<0.001), hepatic abscess in the left lobe (OR = 1.51, 95% CI: 1.02, 2.24, p = 0.039), phlebitis (OR = 21.01, 95% CI: 10.24, 43.11, p<0.001), procalcitonin (PCT) (OR = 1.01, 95% CI: 1.01, 1.02, p<0.001), fasting blood glucose (FBG) (OR = 1.21, 95% CI: 1.11, 1.32, p<0.001), prothrombin time (PT) (OR = 1.15, 95% CI: 1.01, 1.30, p = 0.032), total bilirubin (OR = 1.02, 95% CI: 1.01, 1.02, p<0.001), hypervirulent phenotype (OR = 2.17, 95% CI: 1.15, 4.10, p = 0.017), K1 serotype (OR = 4.79, 95% CI: 1.79, 12.76, p = 0.002). No other risk factors were found. Conclusion: This study identified multiple risk factors significantly associated with IKPLAS, providing evidence for risk assessment and prevention strategies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.